Investigating the effects of Salmeterol on exercise performance in healthy individuals
The Muscle Anabolic Response to β2-adrenergic Stimulation
This study is testing if the medication Salmeterol can improve exercise performance and muscle growth in healthy young adults who work out regularly.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 36 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | University of Copenhagen Academic / other |
| Locations | 1 site (Copenhagen) |
| Trial ID | NCT06655012 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the muscle anabolic response to acute beta2-adrenergic stimulation using Salmeterol in young, healthy men and women. Participants will be physically active individuals aged 18-40 who engage in more than five hours of exercise per week. The study will compare the effects of Salmeterol against a placebo to assess its impact on exercise performance and muscle response. The research is conducted at the University of Copenhagen, focusing on understanding how beta2-adrenergic stimulation can enhance muscle hypertrophy.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy, physically active individuals aged 18-40 with high levels of aerobic fitness.
Not a fit: Patients who are smokers, have chronic illnesses, or are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into enhancing exercise performance and muscle growth through pharmacological means.
How similar studies have performed: While the specific approach of using Salmeterol for this purpose may be novel, previous studies have shown that beta2-adrenergic stimulation can influence muscle growth and performance.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion Criteria: * Age 18-40 * Physically active \>5 hours a week * Maximum oxygen uptake classified as high or very high Exclusion Criteria: * Active smoker currently or within the past 5 years * Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women) * Chronic or acute illness deemed by the responsible study physician to affect the test parameters * Deviation from the study protocol * Lean mass index \>21 kg/m² * Pregnancy * Smoker * Blood donation during the past 3 months
Where this trial is running
Copenhagen
- August Krogh Building — Copenhagen, Denmark (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.