Investigating the effects of Salmeterol on exercise performance in healthy individuals
Official title: The Muscle Anabolic Response to β2-adrenergic Stimulation
Run by University of Copenhagen · NCT06655012 · Data updated 2026-11-12
This study is testing if the medication Salmeterol can improve exercise performance and muscle growth in healthy young adults who work out regularly.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | University of Copenhagen Academic / other |
| Locations | 1 site (Copenhagen) |
| Status | Recruiting |
| Started | October 31, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 9, 2025 |
| Trial ID | NCT06655012 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy, physically active individuals aged 18-40 with high levels of aerobic fitness.
✕Probably not a fit
Patients who are smokers, have chronic illnesses, or are pregnant will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to explore the muscle anabolic response to acute beta2-adrenergic stimulation using Salmeterol in young, healthy men and women. Participants will be physically active individuals aged 18-40 who engage in more than five hours of exercise per week. The study will compare the effects of Salmeterol against a placebo to assess its impact on exercise performance and muscle response. The research is conducted at the University of Copenhagen, focusing on understanding how beta2-adrenergic stimulation can enhance muscle hypertrophy.
Why it matters
Potential benefit: If successful, this study could provide insights into enhancing exercise performance and muscle growth through pharmacological means.
How similar studies have gone: While the specific approach of using Salmeterol for this purpose may be novel, previous studies have shown that beta2-adrenergic stimulation can influence muscle growth and performance.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion Criteria: * Age 18-40 * Physically active \>5 hours a week * Maximum oxygen uptake classified as high or very high Exclusion Criteria: * Active smoker currently or within the past 5 years * Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women) * Chronic or acute illness deemed by the responsible study physician to affect the test parameters * Deviation from the study protocol * Lean mass index \>21 kg/m² * Pregnancy * Smoker * Blood donation during the past 3 months
Where it's running
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August Krogh Building
Copenhagen, Denmark Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.