Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Investigating the effects of Salmeterol on exercise performance in healthy individuals

Official title: The Muscle Anabolic Response to β2-adrenergic Stimulation

Run by University of Copenhagen · NCT06655012 · Data updated 2026-11-12

This study is testing if the medication Salmeterol can improve exercise performance and muscle growth in healthy young adults who work out regularly.

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Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment36 (estimated)
SponsorUniversity of Copenhagen
Academic / other
Locations1 site (Copenhagen)
StatusRecruiting
StartedOctober 31, 2024
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedApril 9, 2025
Trial IDNCT06655012 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy, physically active individuals aged 18-40 with high levels of aerobic fitness.

Probably not a fit

Patients who are smokers, have chronic illnesses, or are pregnant will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the muscle anabolic response to acute beta2-adrenergic stimulation using Salmeterol in young, healthy men and women. Participants will be physically active individuals aged 18-40 who engage in more than five hours of exercise per week. The study will compare the effects of Salmeterol against a placebo to assess its impact on exercise performance and muscle response. The research is conducted at the University of Copenhagen, focusing on understanding how beta2-adrenergic stimulation can enhance muscle hypertrophy.

Why it matters

Potential benefit: If successful, this study could provide insights into enhancing exercise performance and muscle growth through pharmacological means.

How similar studies have gone: While the specific approach of using Salmeterol for this purpose may be novel, previous studies have shown that beta2-adrenergic stimulation can influence muscle growth and performance.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inclusion Criteria:
* Age 18-40
* Physically active \>5 hours a week
* Maximum oxygen uptake classified as high or very high

Exclusion Criteria:

* Active smoker currently or within the past 5 years
* Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
* Chronic or acute illness deemed by the responsible study physician to affect the test parameters
* Deviation from the study protocol
* Lean mass index \>21 kg/m²
* Pregnancy
* Smoker
* Blood donation during the past 3 months

Where it's running

  • August Krogh Building
    Copenhagen, Denmark
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.