Investigating the effects of remote ischemic preconditioning on blood characteristics in healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore how remote ischemic preconditioning (RIPC) affects the peripheral blood characteristics of healthy adults. It will recruit 60 volunteers who will be randomly assigned to either a high-frequency or low-frequency RIPC group. The high-frequency group will undergo RIPC twice daily for seven days, while the low-frequency group will participate once daily. Blood samples will be collected before, during, and after the training to analyze changes in blood components and understand the mechanisms behind RIPC's protective effects on the cardiovascular system.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18 to 45 years;
* Be in good health;
* Consent to participate in the clinical trial and sign the informed consent form.

Exclusion Criteria:

* Abnormal results in biochemical checks and physiological indicators.
* Cardiovascular and cerebrovascular diseases: hypertension, coronary heart disease, congenital heart disease, cerebrovascular alterations, etc.
* Endocrine diseases: diabetes, thyroid disorders, etc.
* Hematologic diseases: anemia, paroxysmal hemoglobinuria, primary thrombocytosis, etc.
* Infectious diseases: hepatitis B, hepatitis C, syphilis, etc.
* Cancer.
* Neurological and psychiatric disorders.
* Vascular diseases: peripheral vascular disease, Raynaud's syndrome, thromboembolic diseases.
* Major trauma or surgery within the last six months.
* Pregnant or breastfeeding women.
* Upper limbs unsuitable for compression treatment: history of upper limb surgery, presence of tissue damage and limb deformity, and concomitant hemorrhagic diseases.
* Recent circumstances that may affect results: blood donors within the last month, any medication taken within the last month, fever within the last week, women within their menstrual cycle or within 7 days before the start of menstruation.
* Patients who refuse to sign the informed consent form for participation in this study.

Where it's running

• First Affiliated Hospital of Xian Jiantong University
  Xi'an, Shaanxi, China Recruiting

Study contacts

• Principal investigator: Guoliang Li — First Affiliated Hospital Xi'an Jiaotong University
• Study coordinator: Guoliang Li
• Email: liguoliang_med@163.com
• Phone: 00-86-029-85323805

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Repeated brief limb ischemia to see its effect on blood pressure and inflammation in people with kidney disease

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.