Investigating the effects of hormonal therapy in transsexual individuals
Official title: A European Network for the Investigation of Gender Incongruence
Run by University Hospital, Ghent · NCT01072825 · Data updated 2026-11-12
This study is trying to see how hormonal therapy affects the physical and mental health of transgender individuals across different centers in Europe.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 125 (estimated) |
| Sponsor | University Hospital, Ghent Academic / other |
| Locations | 4 sites (Ghent and 3 other locations) |
| Status | Recruiting |
| Started | February 15, 2010 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | September 21, 2026 |
| Trial ID | NCT01072825 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are transsexual persons over the age of 18 who have not yet started hormonal therapy.
✕Probably not a fit
Patients who are already undergoing hormonal therapy or are under 18 years old may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the physical and psychological effects of hormonal treatment in transsexual persons through a multicenter approach across Europe. It involves standardized protocols for hormonal therapy and includes various assessments such as questionnaires, blood sampling, and clinical evaluations. The study seeks to fill the knowledge gap regarding the impacts of hormonal therapy on this population, which has been insufficiently documented in existing literature.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the effects of hormonal therapy, improving treatment protocols for transsexual individuals.
How similar studies have gone: While there is limited data on similar multicenter studies, the approach of standardizing hormonal protocols is promising and may lead to significant findings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Transsexual persons older then 18 years, who are not yet treated with hormonal therapy. Exclusion Criteria: \-
Where it's running
-
Genderteam UZ Gent
Ghent, Belgium Recruiting - Florence, Italy Recruiting
-
VU University Medical CenterAmsterdam
Amsterdam, Netherlands Recruiting -
Rikshospitalet University Hospital, University of Oslo
Oslo, Norway Recruiting
Study contacts
- Principal investigator: Guy T'Sjoen, MD — University Hospital, Ghent
- Study coordinator: Guy T'Sjoen, MD
- Email: guy.tsjoen@ugent.be
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.