Investigating the effects of hormonal therapy in transsexual individuals

A European Network for the Investigation of Gender Incongruence

Observational University Hospital, Ghent · NCT01072825

This study is trying to see how hormonal therapy affects the physical and mental health of transgender individuals across different centers in Europe.

Quick facts

Study typeObservational
Enrollment125 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Ghent Academic / other
Locations4 sites (Ghent and 3 other locations)
Trial IDNCT01072825 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the physical and psychological effects of hormonal treatment in transsexual persons through a multicenter approach across Europe. It involves standardized protocols for hormonal therapy and includes various assessments such as questionnaires, blood sampling, and clinical evaluations. The study seeks to fill the knowledge gap regarding the impacts of hormonal therapy on this population, which has been insufficiently documented in existing literature.

Who should consider this trial

Good fit: Ideal candidates for this study are transsexual persons over the age of 18 who have not yet started hormonal therapy.

Not a fit: Patients who are already undergoing hormonal therapy or are under 18 years old may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the effects of hormonal therapy, improving treatment protocols for transsexual individuals.

How similar studies have performed: While there is limited data on similar multicenter studies, the approach of standardizing hormonal protocols is promising and may lead to significant findings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Transsexual persons older then 18 years, who are not yet treated with hormonal therapy.

Exclusion Criteria:

\-

Where this trial is running

Ghent and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Physical and Psychological Evaluation of Hormonal Therapy in Transsexual Persons
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.