Investigating the effects of disinfectants on pain and success in dental procedures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of sodium hypochlorite and chlorhexidine as cavity disinfectants during partial caries removal in patients with deep carious lesions and moderate pulpitis. The research will compare the clinical and radiographic outcomes of using these disinfectants against saline in mature permanent mandibular molars. Patients will be monitored for post-operative pain levels and treatment success over a 12-month follow-up period. The study includes a detailed assessment of pain reduction at 24-hour intervals for the first week post-procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The patient should be ≥18 years of age.
2. Restorable mature permanent 1st and 2nd Mandibular molars with extremely deep caries (≥2/3 dentine involvement)
3. Tooth should give positive response to pulp sensibility testing.
4. Clinical diagnosis of moderate pulpitis.
5. Radiographic finding of periapical index (PAI) score ≤2.
6. Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit)

Exclusion Criteria:

Presence of vertical root fracture Presence of root perforations ASA-3 or ASA-4 according to the classification of the American Society of Anesthesiologists) Presence of root resorption Combined endodontic-periodontic lesions. Pregnancy

Where it's running

• Pgids Rohtak
  Haryāna, India Recruiting

Study contacts

• Principal investigator: Dr Sanjay Tewari, MDS — PGIDS Rohtak
• Study coordinator: Dr. Shweta Mittal
• Email: shwetagoelendo@gmail.com
• Phone: 9255596960

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.