Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Investigating the effects of cold atmospheric plasma on peritoneal tumor tissue

Official title: Effects of Cold Atmospheric Plasma (CAP) on Peritoneal Tumor Tissue

Run by University Hospital, Ghent · NCT06796634 · Data updated 2026-11-12

This study is testing if a new treatment using cold plasma can help shrink tumor tissue in patients with peritoneal metastases before surgery.

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Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment5 (estimated)
SponsorUniversity Hospital, Ghent
Academic / other
Locations1 site (Ghent, East-Flanders)
StatusRecruiting
StartedAugust 21, 2024
Main results expectedApril 1, 2025
Study endsApril 1, 2025
Registry record updatedJanuary 28, 2025
Trial IDNCT06796634 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with peritoneal metastases from cancers such as ovarian cancer, colorectal cancer, or malignant peritoneal mesothelioma who are scheduled for surgery.

Probably not a fit

Patients with tumors not located in the peritoneum or those who are not undergoing surgical intervention may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the effects of cold atmospheric plasma (CAP) on tumor tissue in patients with peritoneal metastases undergoing surgery. Tumor nodules will be treated with varying durations and intensities of CAP prior to surgical removal. The resected nodules will then be analyzed to assess tumor vitality and the potential impact of CAP treatment. This innovative approach seeks to provide insights into the efficacy of CAP in targeting tumor cells.

Why it matters

Potential benefit: If successful, this treatment could enhance surgical outcomes and improve survival rates for patients with peritoneal metastases.

How similar studies have gone: This approach is novel, as there are currently no existing studies examining the effects of cold atmospheric plasma on tumor tissue in patients.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Patients with peritoneal metastases undergoing surgery (CRS, debulking), irrespective of the origin. Potential cancer types include ovarian cancer, colorectal cancer, and malignant peritoneal mesothelioma
* Written informed consent
* Age ≥ 18 years.

Where it's running

  • UZ Ghent
    Ghent, East-Flanders, Belgium
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.