Investigating the effects of brain stimulation on emotion regulation in autism
The Therapeutic Effect of TBS Stimulation Over Left Dorsolateral Prefrontal Cortex on Emotion Regulation in Autism Spectrum Disorder
NA · Chang Gung Memorial Hospital · NCT04987541
This study is testing if a new type of brain stimulation can help people with autism manage their emotions better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 8 Years to 30 Years |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital (other) |
| Locations | 1 site (Taoyuan) |
| Trial ID | NCT04987541 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the impact of intermittent theta burst stimulation on the left dorsolateral prefrontal cortex to improve emotion regulation in individuals with autism spectrum disorder. Participants diagnosed with autism will receive this non-invasive brain stimulation treatment to assess its effectiveness. The study will evaluate changes in emotional responses and regulation following the intervention, providing insights into potential therapeutic approaches for autism.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with autism spectrum disorder confirmed by the Autism Diagnostic Observation Schedule (ADOS).
Not a fit: Patients with severe neurological disorders, psychiatric conditions, or other significant health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could enhance emotional regulation in individuals with autism, improving their quality of life.
How similar studies have performed: While the use of theta burst stimulation is a relatively novel approach, preliminary studies have shown promise in similar applications for other conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * autism spectrum disorder, confirmed by ADOS Exclusion Criteria: * Previous or current severe neurological disorder such as epilepsy, visual or hearing impairment * Previous or current severe systemic disease such as cardiovascular disease, diabetes or infection * Previous or current severe brain injury * Implementation of metal materials such as pacemaker or medication pump * Previous or current severe psychiatric disorders such as schizophrenia, bipolar disorder or substance abuse * Pregnancy * Individuals with a significant brain abnormality such as intracranial space occupied lesions * Individuals with a family history of epilepsy * Previous febrile seizures * Current taking antiepileptic drugs * Concurrent use of medications which increased the risk of seizure attack * Individuals suffering from sleep deprivation during rTMS procedures * Skin trauma on application site * Any condition which in the Investigator's opinion deems the participant an unsuitable candidate to participate in the study * Participate another clinical trial within one month
Where this trial is running
Taoyuan
- Chang Gung Memorial Hospital — Taoyuan, Taiwan (RECRUITING)
Study contacts
- Study coordinator: Hsing-Chang Ni, Dr.
- Email: alanni0918@yahoo.com.tw
- Phone: 88633281200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Autism Spectrum Disorder