Investigating the effects of a sedation drug on cognition in elderly patients during colonoscopy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate how Remimazolam tosilate affects cognitive function in elderly patients undergoing colonoscopy. The study compares the cognitive outcomes of patients sedated with Remimazolam to those receiving Propofol and saline solution. By focusing on older adults, the trial seeks to address potential cognitive impairments associated with sedation during medical procedures. Participants will be carefully selected based on specific inclusion and exclusion criteria to ensure the validity of the results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. ASA I\~II
2. patients will be treatmented by sedation under colonoscopy
3. sign informed consent

Exclusion Criteria:

(1) Preoperative depression and cognitive impairment

（2） Hearing or visual impairment;

（3） Drug abuse, alcoholism or long-term use of antidepressants;

（4） Cardiovascular and cerebrovascular accidents, neurological sequelae, or severe liver and kidney function damage occurred within 6 months

（5） BMI \< 18, BMI \> 30

（6） Confirmed or suspected allergy to the test drug

Where it's running

• Yongming Chen
  Shanghai, Shanghai, China Recruiting

Study contacts

• Study coordinator: chen yongming, MD
• Email: chelman@outlook.com
• Phone: 13564932181

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.