Investigating the eating habits of young adults
Influence of Ultra-processed Foods on Reward Processing and Energy Intake
This study tests how eating ultra-processed foods affects the eating habits and brain function of young adults aged 18-25.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 18 Years to 25 Years |
| Sex | All |
| Sponsor | Virginia Polytechnic Institute and State University Academic / other |
| Locations | 2 sites (Blacksburg, Virginia and 1 other locations) |
| Trial ID | NCT05550818 on ClinicalTrials.gov |
What this trial studies
This research aims to understand how ultra-processed foods affect eating behaviors and brain function in young adults aged 18-25. Participants will follow two different diets: one high in ultra-processed foods and another emphasizing minimally processed foods, over two 14-day periods. The study will measure changes in energy intake, brain responses to food, and executive function. By exploring these factors, the research seeks to establish a proof-of-concept regarding the impact of diet on health outcomes in this age group.
Who should consider this trial
Good fit: Ideal candidates for this study are young adults aged 18-25 who are weight stable and willing to adhere to the dietary protocols.
Not a fit: Patients with a BMI over 30 or those with significant health issues such as chronic diseases or eating disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved dietary recommendations and interventions for young adults to promote healthier eating habits and prevent obesity.
How similar studies have performed: While there is evidence from pre-clinical studies on the effects of ultra-processed diets, this specific approach in humans is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-25 years * Weight stable (+5 lbs) for previous 6 months * No plans to gain/lose weight or change physical activity level * Willing to pick up food daily and consume foods provided for two 14-day periods * Verbal and written informed consent * Unrestrained eater (TFEQ cognitive restraint score \<11) * No reported history of eating disorders * Sedentary to recreationally active * ADHD medications if same med \>3 months at time of study Exclusion Criteria: * BMI \>30 kg/m2 * Endocrine disorders or other major chronic disease (e.g., type 2 diabetes, hypothyroidism, hypertension) * Pregnant or plans to become pregnant * Food allergies or aversions * Claustrophobia * History of head injury with loss of consciousness for more than 10 minutes * Contraindications to MRI: individuals with pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, steel worker, or other implants.
Where this trial is running
Blacksburg, Virginia and 1 other locations
- Virginia Polytechnic Institute and State University — Blacksburg, Virginia, United States (Recruiting)
- Fralin Biomedical Research Institute at VTC — Roanoke, Virginia, United States (Recruiting)
Study contacts
- Principal investigator: Alexandra G DiFeliceantonio, PhD — Virginia Polytechnic Institute and State University
- Study coordinator: Brenda M Davy, PhD, RDN
- Email: davy@vt.edu
- Phone: 540-231-6784
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.