Investigating the causes and treatment of high calcium levels from paraffin oil injections

Hypercalcemia After Cosmetic Paraffin Oil Injections: Unravelling Etiology, Pathogenesis and Potential Treatments

Observational Herlev Hospital · NCT04265599

This study looks at the health issues caused by paraffin oil injections to see how they affect people and to help find new treatments for those problems.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorHerlev Hospital Academic / other
Locations1 site (Copenhagen)
Trial IDNCT04265599 on ClinicalTrials.gov

What this trial studies

This observational study aims to characterize the granulomatous disease caused by intramuscular injections of paraffin oil, focusing on the pathogenesis and natural history of the condition. By understanding these aspects, the study seeks to lay the groundwork for identifying novel treatments that can be tested in future randomized clinical trials. The research will involve collecting data from patients who have previously received such injections to better understand the implications of paraffin oil on health.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals who have previously received intramuscular injections of paraffin or other oils.

Not a fit: Patients who have not received intramuscular injections of paraffin or other oils may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to new treatment options for patients suffering from hypercalcemia and related conditions caused by paraffin oil injections.

How similar studies have performed: While this study explores a specific condition, similar observational studies have provided valuable insights into treatment pathways for related diseases, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* previous intramuscular injection of paraffin or other oil

Exclusion Criteria:

* none

Where this trial is running

Copenhagen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HypercalcemiaRenal InjuryParaffinoma
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.