Investigating thalidomide's effects on beta thalassemia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the safety and efficacy of low-dose thalidomide in managing transfusion-dependent beta thalassemia, a genetic blood disorder. Conducted over two years at the National Institute of Blood Disease and Bone Marrow Transplant in Karachi, it involves 54 patients aged 8-35. The primary goal is to correlate different doses of thalidomide with disease severity, treatment response, and adverse effects. Data will be collected through clinical interviews and medical record reviews, focusing on key health indicators such as hemoglobin levels and transfusion frequency.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Know case of beta thalassemia major/ intermediate ( transfusion dependent)
* willing to give informed consent

Exclusion Criteria:

* Patients with comorbidities such as liver dysfunction
* Married patients
* Lactating mother
* H/O thrombosis and fits

Where it's running

• National Institute of blood disease and bone marrow transplant
  Karachi, Sindh, Pakistan Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.