Investigating testosterone treatment effects in transgender men and non-binary individuals
Masculinizing Testosterone Treatment and Effects on Preclinical Cardiovascular Disease, Muscle Strength and Power, Aggression, Physical Fitness and Respiratory Function in Transgender Men,Body Identity Clinic (BIC)
This study is testing how testosterone treatment affects the health and well-being of transgender men and non-binary individuals over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Odense University Hospital Academic / other |
| Locations | 1 site (Odense) |
| Trial ID | NCT04254354 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the effects of testosterone treatment on transgender men and non-binary persons, focusing on various health aspects such as cardiovascular status, muscle strength, aggression, and quality of life. Conducted at the Body Identity Clinic in Denmark, participants will be monitored before and during testosterone therapy over a period of up to ten years. The study seeks to understand the potential development of non-calcified coronary plaque associated with testosterone treatment, contributing to the ongoing discussion about its short- and long-term effects.
Who should consider this trial
Good fit: Ideal candidates for this study are transgender men and non-binary persons seeking testosterone treatment.
Not a fit: Patients who are not transgender men or non-binary individuals may not receive any benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the health impacts of testosterone treatment, guiding safer and more effective care for transgender individuals.
How similar studies have performed: While there is ongoing research in this area, the specific focus on cardiovascular effects and non-calcified coronary plaque in this population is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Transgender men Exclusion Criteria: none
Where this trial is running
Odense
- Odense University Hospital — Odense, Denmark (Recruiting)
Study contacts
- Principal investigator: Marianne Andersen — Odense University Hospital
- Study coordinator: marianne andersen, Professor
- Email: msa@rsyd.dk
- Phone: +4565412502
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.