Investigating testosterone treatment effects in transgender men and non-binary individuals

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the effects of testosterone treatment on transgender men and non-binary persons, focusing on various health aspects such as cardiovascular status, muscle strength, aggression, and quality of life. Conducted at the Body Identity Clinic in Denmark, participants will be monitored before and during testosterone therapy over a period of up to ten years. The study seeks to understand the potential development of non-calcified coronary plaque associated with testosterone treatment, contributing to the ongoing discussion about its short- and long-term effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Transgender men

Exclusion Criteria:

none

Where it's running

• Odense University Hospital
  Odense, Denmark Recruiting

Study contacts

• Principal investigator: Marianne Andersen — Odense University Hospital
• Study coordinator: marianne andersen, Professor
• Email: msa@rsyd.dk
• Phone: +4565412502

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• How male-level testosterone affects reproductive hormone cycles in people assigned female at birth

  This study will test whether male-level testosterone given to transgender men starting hormone therapy changes the ovarian and pituitary hormones that control menstrual cycles compared with cisgender women.

  Recruiting Phase 4 University of California, San Diego · San Diego, California · NCT07092527

• Evaluating voice outcomes after gender-affirming voice surgeries

  This study is testing how different gender-affirming voice surgeries affect voice quality and patient satisfaction over time.

  Recruiting at 2 sites University Ghent · Ghent, East-Flanders and 1 other locations · NCT06439290

• Assessing pelvic changes after vaginoplasty in transgender women

  This study is testing how the body changes after vaginoplasty in transgender women to see how well the surgery works and what effects it has over time.

  Recruiting University Hospital, Limoges · Limoges, Limoges · NCT06093724

• Examining the effects of hormone treatment in transgender women and non-binary individuals

  This study is testing how hormone treatment affects heart health over time in transgender women and non-binary individuals.

  Recruiting Odense University Hospital · Odense · NCT05169762

• Effects of cross-sex hormone therapy on metabolism and eating behavior

  This study looks at how cross-sex hormone therapy affects metabolism, eating habits, and overall health in people undergoing this treatment.

  Recruiting University of Leipzig · Leipzig, Saxony · NCT04838249

• Effects of Estradiol on Cardiometabolic Health in Transgender Youth

  This study tests how estradiol affects insulin sensitivity and blood vessel health in transgender girls aged 13-16 compared to girls who are not transgender.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT04596592

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.