Investigating taste responses in obese individuals before and after weight loss surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the neuro-anatomical responses to gastrointestinal taste stimulation in morbidly obese individuals by using functional MRI. Participants will receive intragastric administration of glucose, monosodium glutamate, chloroquine, and a placebo, followed by brain imaging before and three months after undergoing bariatric surgery. The goal is to understand how bariatric surgery affects taste perception and related brain activity in obese patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* morbidly obese patients (BMI min 35kg/m2) scheduled for bariatric surgery
* right handed

Exclusion Criteria:

* cardiovascular disease
* neurologic/psychiatric disorders

Where it's running

• University Hopital Basel
  Basel, Switzerland Recruiting

Study contacts

• Study coordinator: Bettina Wölnerhanssen, Dr
• Email: bettina.woelnerhanssen@usb.ch

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.