Investigating spinal CSF leaks in patients with chronic subdural hematoma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with chronic subdural hematoma (cSDH), a condition characterized by the accumulation of blood and fluid between the brain and its outer covering. The research aims to explore the potential link between spinal cerebrospinal fluid (CSF) leaks and the development of cSDH, which is often underdiagnosed. Participants will undergo imaging studies such as CT or MRI to confirm the presence of cSDH and assess the underlying causes. The study seeks to improve understanding of cSDH and its complications, potentially leading to better diagnostic and treatment strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Chronic subdural hematoma on imaging (CT/MRI)
2. Age: 18 years or older
3. Informed consent

Exclusion Criteria:

1. General contraindications for MRI examination (e.g., pacemaker wearers, implanted insulin, or pain pump, neurostimulator, etc.)
2. Recurrent chronic subdural hematoma and previously performed diagnostics and treatment in compliance to the current cSDH SOP
3. Severe brain injury, acute subdural hematoma, epidural hematoma, subarachnoid hemorrhage

Where it's running

• University of Freiburg
  Freiburg im Breisgau, Baden-Wurttemberg, Germany Recruiting

Study contacts

• Principal investigator: Jürgen Beck, Prof. — Department of Neurosurgery, Medical Center, University of Freiburg
• Study coordinator: Katharina Wolf, Dr.
• Email: katharina.wolf@uniklinik-freiburg.de
• Phone: +4976127093556

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Middle Meningeal Artery Embolisation to Prevent Recurrence of Chronic Subdural Hematoma

  This study tests whether embolising the middle meningeal artery around the time of hematoma evacuation can reduce recurrence in adults with chronic subdural hematoma.

  Recruiting at 6 sites University Hospital Hradec Kralove · České Budějovice and 5 other locations · NCT07751887

• What causes vulnerability in older adults with serious diseases and how it affects care decisions

  This study tests how often vulnerability factors appear in older adults with serious illnesses and how these factors influence treatment timing, survival, and quality of life.

  Recruiting Tampere University Hospital · Tampere · NCT07740239

• Coil embolization for unilateral vs bilateral chronic subdural hematomas

  This trial tests whether unilateral or bilateral coil-based embolization of the middle meningeal artery helps people with chronic subdural hematoma.

  Recruiting Lahey Clinic · Burlington, Massachusetts · NCT07715656

• Non-Thermal Plasma Used During Surgery to Help Prevent Recurrent Chronic Subdural Hematoma

  A randomized trial tests whether applying non-thermal plasma during standard surgery to drain a chronic subdural hematoma can reduce recurrence within 6 months.

  Recruiting National Institute of Nuclear Research - Mexico · Ocoyoacac, State of Mexico · NCT07656818

• Enhanced recovery pathway for burr-hole drainage in chronic subdural hematoma patients

  This project tests whether an enhanced recovery protocol for adults having burr-hole drainage for chronic subdural hematoma can reduce recurrence and complications compared with past patients.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07421453

• Matched microcatheter and guidewire use for middle meningeal artery embolization in chronic subdural hematoma

  This will test whether using a matched Aristotle 14 guidewire and Plato 17 microcatheter during middle meningeal artery embolization works better than surgeons' usual device choices for adults with chronic subdural hematoma.

  Recruiting Ohio State University · Columbus, Ohio · NCT07324551

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.