Investigating sex differences in blood pressure control in obstructive sleep apnea patients
Sex Differences in Neurocirculatory Control With Obstructive Sleep Apnea
This study looks at how being male or female might change blood pressure control in people with untreated obstructive sleep apnea to help improve treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 20 Years to 70 Years |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06261034 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore how sex differences may affect neurocirculatory control of blood pressure in individuals suffering from untreated obstructive sleep apnea (OSA). By examining a diverse group of participants aged 20 to 70, the study will analyze physiological responses and potential variations between male and female patients. The findings could enhance understanding of OSA's impact on cardiovascular health and inform tailored treatment approaches.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 20 to 70 who have been diagnosed with untreated obstructive sleep apnea.
Not a fit: Patients with significant comorbidities such as coronary artery disease, heart failure, or other sleep disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for obstructive sleep apnea that consider sex-specific differences.
How similar studies have performed: While the investigation of sex differences in neurocirculatory control is a relatively novel approach, similar studies have shown promising results in understanding gender-specific health issues.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 20-70 years of age Exclusion Criteria: * Coronary artery disease * Heart failure * Pregnancy * COPD * Diabetes * CKD * Sleep disorders other than OSA * Shift workers * Individuals who typically go to sleep after midnight * Individuals who traveled across ≥2 time zones within one week of study visits * BMI ≥40.0kg/m2 * Use of nicotine-containing products within the two years preceding study visits * Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with outcome measures
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Joshua Bock, PhD — Mayo Clinic
- Study coordinator: Joshua Bock, PhD
- Email: Bock.Joshua@mayo.edu
- Phone: (507) 422-0768
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.