Investigating risk factors for sepsis after ERCP procedures
Intra-operative Hypotension and Sepsis After Endoscopic Retrograde Cholangiopancreatography: A Prospective Cohort Study
This study is trying to see if low blood pressure during or right after an ERCP procedure is linked to a higher chance of getting sepsis in patients with obstructive jaundice.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mansoura University Academic / other |
| Locations | 1 site (Mansoura, Aldakahlia) |
| Trial ID | NCT06187168 on ClinicalTrials.gov |
What this trial studies
This observational cohort study aims to explore the relationship between unexplained hypotension during or shortly after endoscopic retrograde cholangiopancreatography (ERCP) and the occurrence of post-ERCP sepsis. Conducted at the Gastrointestinal Surgery Centre of Mansoura University in Egypt, the study will involve 50 adult patients undergoing ERCP for obstructive jaundice. The primary outcome measure will be the incidence of post-ERCP sepsis, while other related complications will also be assessed. The findings are expected to enhance understanding of ERCP-related risks and inform better patient management strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who are undergoing ERCP for obstructive jaundice.
Not a fit: Patients who are already experiencing sepsis prior to the ERCP or are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention strategies for post-ERCP sepsis, enhancing patient safety and outcomes.
How similar studies have performed: While the specific relationship between hypotension and post-ERCP sepsis is not widely studied, similar observational studies have shown promising results in understanding complications related to surgical procedures.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing ERCP for obstructive jaundice * Adult (Older than 18 years old) * Written Informed Consent Exclusion Criteria: * Already on sepsis before the ERCP * Pregnancy
Where this trial is running
Mansoura, Aldakahlia
- Mansoura Univesity Faculty of Medicine — Mansoura, Aldakahlia, Egypt (Recruiting)
Study contacts
- Study coordinator: Moataz M Emara, MD, EDAIC
- Email: mm.emara@mans.edu.eg
- Phone: +201064048848
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.