Clinical trial No longer in our active list Observational Ages 18 and up

Investigating retinal damage in COVID-19 patients using non-invasive imaging

Official title: COVID-19 Patient Cohort: Retinal Damage in Non-invasive Retinal Imaging (OCTA)

Run by Centre Hospitalier Intercommunal Creteil · NCT04881253 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if COVID-19 can cause damage to the eyes by using special imaging techniques on patients with different levels of illness.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorCentre Hospitalier Intercommunal Creteil
Academic / other
Locations1 site (Créteil, IDF)
Trial IDNCT04881253 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who have been diagnosed with COVID-19.

Probably not a fit

Patients who do not have a confirmed diagnosis of COVID-19 or those who refuse to participate will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect non-invasive retinal imaging data, specifically using optical coherence tomography (OCT) and OCT angiography (OCTA), to assess the incidence and impact of retinal damage in patients with COVID-19. It includes three groups of participants: those hospitalized for COVID-19, newly diagnosed patients, and those with mild symptoms who did not require hospitalization. An ophthalmologic assessment will be conducted at inclusion, which includes visual acuity tests and various imaging techniques to detect potential retinal lesions. The study seeks to correlate clinical parameters with retinal vascular damage to enhance understanding of the disease's pathophysiology.

Why it matters

Potential benefit: If successful, this study could provide insights into the retinal complications associated with COVID-19, potentially leading to better management and treatment strategies for affected patients.

How similar studies have gone: While this study focuses on a specific aspect of COVID-19, similar studies investigating retinal damage in other conditions have shown promising results, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years old
* Diagnosis of COVID-19 proven on RT-PCR, antigenic test or chest CT scan
* Affiliation to the general social security system
* A consent signed by the patient

Exclusion Criteria:

- Refusal of patient participation

Where it's running

  • Centre Hospitalier Intercommunal de Créteil
    Créteil, Idf, France
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.