Investigating resistance training effort in type 2 diabetes management
The Effect of Perceived Effort in Resistance Training on Glycemic Control and Psychological Responses in Individuals Living With Type 2 Diabetes Mellitus: a Randomized-controlled, Parallel Group, Clinical Trial
This study tests whether putting in more or less effort during resistance training can help people with type 2 diabetes manage their blood sugar and feel better mentally.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 48 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | University of New Mexico Academic / other |
| Drugs / interventions | rituximab |
| Locations | 1 site (Albuquerque, New Mexico) |
| Trial ID | NCT06497842 on ClinicalTrials.gov |
What this trial studies
This study aims to explore how different levels of effort during resistance exercise training affect glycemic control and psychological responses in individuals with type 2 diabetes mellitus. It will compare high-effort and low-effort resistance training to determine their impact on glucose metabolism and insulin sensitivity. Additionally, the study will assess adherence rates and reasons for dropout among participants, providing insights into the motivational aspects of exercise for this population.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals living with type 2 diabetes mellitus who are capable of performing resistance exercises.
Not a fit: Patients with significant cognitive impairments, severe cardiovascular issues, or other serious health conditions that prevent them from engaging in resistance training may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance exercise prescriptions for individuals with type 2 diabetes, leading to better glycemic control and improved adherence to exercise regimens.
How similar studies have performed: While there is existing evidence supporting the benefits of resistance training for diabetes management, this specific investigation into varying degrees of effort is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Living with type 2 diabetes mellitus Exclusion Criteria: * Have a significant cognitive impairment, * Are non-ambulatory, * Have lower extremity amputation, * Have renal failure, * Have liver disease, * Have uncontrolled hypertension (\>160 mmHg systolic and/or \>100 mmHg diastolic), * Have unstable cardiovascular disease, * Have a history of severe cardiovascular problems, * Have decompensated heart failure, * Have uncontrolled arrhythmias, * Have severe pulmonary hypertension (mean pulmonary arterial pressure \>55 mm Hg), * Have severe and symptomatic aortic stenosis, * Have acute myocarditis, endocarditis, or pericarditis, * Have aortic dissection, * Have Marfan syndrome, * Have unrepaired aortic aneurysm, * Have proliferative diabetic retinopathy, * Have rapidly progressive terminal illness, * Are unable to perform resistance exercise to due preexisting musculoskeletal conditions (e.g., joint pain, chronic injury or tendinopathy), * Are under biguanide (metformin) treatment, but are taking for less than 3 months, * Have taken drugs known to increase the risk of tendon disorders (e.g., tendinopathy and tendon rupture) within the last 6 months. These drugs include, but may not be limited to: fluoroquinolones, glucocorticoids, aromatase inhibitors, anabolic steroids, antiretrovirals, isotretinoin, cephalexin, rituximab, sitagliptin, cephalosporins, azithromycin, and sulfonamides. * Are pregnant or trying to become pregnant during the study, * Are prisoners, * Are persons that require a legally authorized representative. Temporary exclusions include: * Being subjected to recent surgeries for which resistance training is not recommended, * Have symptomatic hernias, * Have acute illness, * Have recent fractures, or other injuries until resolved.
Where this trial is running
Albuquerque, New Mexico
- UNM Exercise Physiology Lab — Albuquerque, New Mexico, United States (Recruiting)
Study contacts
- Principal investigator: Flavio De Castro Magalhaes, PhD — Assistant Professor
- Study coordinator: Roberto Mota Alvidrez, MD / PhD
- Email: RMotaAlvidrez@salud.unm.edu
- Phone: 505-415-8005
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.