Investigating reconstruction methods after pelvic cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients undergoing pelvic cancer surgeries, specifically pelvic exenteration and abdominoperineal excision. It aims to collect and analyze data on complication rates, quality of life, and healthcare resource utilization associated with various reconstruction techniques. The study includes maintaining a comprehensive database, conducting a national collaborative study, and performing qualitative interviews to gather patient experiences. By evaluating these factors, the research seeks to enhance decision-making for patients and healthcare providers regarding reconstruction options.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male and female patients aged 18 or older
* Patients that have undergone pelvic exenteration or abdominoperineal excision at participating sites, at any time, that have complete data (work package 1 - Colorectal Surgery Database)
* Patients undergoing pelvic exenteration or abdominoperineal excision at participating sites (work package 2 - prospective study)
* Patients that have already had pelvic exenteration or abdominoperineal resection that can speak English (work package 3 - mixed-methods study)

Exclusion Criteria:

* Patients eligible for, but that are unfit, decline or are not offered abdominoperineal excision or pelvic exenteration surgery
* Patients that undergo surgery by an intersphincteric abdominoperineal resection approach
* Patients that are unable to complete the questionnaire over the telephone or online with a researcher
* Patients unable or unwilling to provide informed consent
* Patients that are prisoners in the custody of HM Prison Service or who are offenders supervised by the probation service

Where it's running

• University Hospital Southampton NHS Foundation Trust
  Southampton, Hampshire, United Kingdom Recruiting
• Salisbury NHS Foundation Trust
  Salisbury, Wiltshire, United Kingdom Recruiting
• Hampshire Hospitals NHS Foundation Trust
  Basingstoke, United Kingdom Recruiting
• Dorset County Hospital NHS Foundation Trust
  Dorchester, United Kingdom Recruiting
• Leeds Teaching Hospitals NHS Trust
  Leeds, United Kingdom Recruiting
• The Newcastle upon Tyne Hospitals NHS Foundation Trust
  Newcastle, United Kingdom Recruiting

Study contacts

• Principal investigator: Kashuf Khan, MBBS MRCS — University Hospitals Southampton
• Study coordinator: Charles West, MBBS BSc
• Email: charles.west4@nhs.net
• Phone: +442381208632

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.