Investigating pancreatic islets in patients undergoing partial pancreatectomy
Official title: Study on the Function of Insulin-producing Beta Cells in the Human Pancreas
Run by German Diabetes Center · NCT06150690 · Data updated 2026-11-12
This study is trying to understand how diabetes affects insulin-producing cells in the pancreas by looking at tissue samples from patients having part of their pancreas removed.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | German Diabetes Center Academic / other |
| Locations | 1 site (Düsseldorf, North Rhine-Westphalia) |
| Status | Recruiting |
| Started | August 21, 2012 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2035 |
| Registry record updated | November 29, 2023 |
| Trial ID | NCT06150690 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients undergoing partial pancreatectomy who can provide informed consent.
✕Probably not a fit
Patients who are unable to give informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study examines the mechanisms behind diabetes by analyzing the structural and functional properties of pancreatic islets in patients who are undergoing partial pancreatectomy. It focuses on detailed assessments of the morphological and functional characteristics of insulin-producing beta cells in human pancreatic tissue samples. By collecting biopsy specimens and clinical data, the study aims to identify diabetes-associated alterations at cellular and molecular levels, contributing to a better understanding of diabetes pathogenesis.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of diabetes mechanisms, potentially leading to improved treatments.
How similar studies have gone: While this study explores a specific aspect of diabetes pathogenesis, similar studies have shown promise in understanding the cellular mechanisms of diabetes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: ability to give informed consent Exclusion Criteria: denial of informed consent
Where it's running
-
German Diabetes Center
Düsseldorf, North Rhine-Westphalia, Germany Recruiting
Study contacts
- Principal investigator: Michael Roden, Prof MD — German Diabetes Center
- Study coordinator: Volker Burkart, PhD
- Email: volker.burkart@ddz.de
- Phone: +49-211-3382
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.