Investigating pancreatic islets in patients undergoing partial pancreatectomy
Study on the Function of Insulin-producing Beta Cells in the Human Pancreas
This study is trying to understand how diabetes affects insulin-producing cells in the pancreas by looking at tissue samples from patients having part of their pancreas removed.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | German Diabetes Center Academic / other |
| Locations | 1 site (Düsseldorf, North Rhine-Westphalia) |
| Trial ID | NCT06150690 on ClinicalTrials.gov |
What this trial studies
This study examines the mechanisms behind diabetes by analyzing the structural and functional properties of pancreatic islets in patients who are undergoing partial pancreatectomy. It focuses on detailed assessments of the morphological and functional characteristics of insulin-producing beta cells in human pancreatic tissue samples. By collecting biopsy specimens and clinical data, the study aims to identify diabetes-associated alterations at cellular and molecular levels, contributing to a better understanding of diabetes pathogenesis.
Who should consider this trial
Good fit: Ideal candidates include patients undergoing partial pancreatectomy who can provide informed consent.
Not a fit: Patients who are unable to give informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of diabetes mechanisms, potentially leading to improved treatments.
How similar studies have performed: While this study explores a specific aspect of diabetes pathogenesis, similar studies have shown promise in understanding the cellular mechanisms of diabetes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: ability to give informed consent Exclusion Criteria: denial of informed consent
Where this trial is running
Düsseldorf, North Rhine-Westphalia
- German Diabetes Center — Düsseldorf, North Rhine-Westphalia, Germany (Recruiting)
Study contacts
- Principal investigator: Michael Roden, Prof MD — German Diabetes Center
- Study coordinator: Volker Burkart, PhD
- Email: volker.burkart@ddz.de
- Phone: +49-211-3382
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.