Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating NFL Levels in Patients After Cardiac Arrest

Official title: Dynamics of Light Chain of NFL as a Predictor Factor of Neurological Outcome in Patients With Out of Hospital Cardiac Arrest

Run by University Medical Centre Maribor · NCT05218278 · Data updated 2026-11-12

This study is testing if measuring a specific protein in the blood can help doctors understand how well patients recover after being resuscitated from a cardiac arrest.

More Out-Of-Hospital Cardiac Arrest trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorUniversity Medical Centre Maribor
Academic / other
Locations1 site (Maribor)
StatusRecruiting
StartedJanuary 1, 2022
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedMarch 30, 2025
Trial IDNCT05218278 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults who have experienced out-of-hospital cardiac arrest and have been successfully resuscitated and admitted to the ICU.

Probably not a fit

Patients who have experienced cardiac arrest due to trauma, drowning, or electrocution, or those under 18 years of age may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the pharmacodynamics of neurofilament light chain (NFL) in patients who have experienced out-of-hospital cardiac arrest and have been successfully resuscitated. It will measure serum levels of NFL at various time points after ICU admission to assess differences between patients with favorable and non-favorable neurological outcomes. By analyzing these levels, the study seeks to identify potential biomarkers that could predict neurological recovery in this patient population.

Why it matters

Potential benefit: If successful, this study could provide a new biomarker for predicting neurological outcomes in patients after cardiac arrest.

How similar studies have gone: While the specific approach of measuring NFL levels in this context may be novel, similar studies have shown promise in using biomarkers to predict neurological outcomes after cardiac events.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* out-of-hospital cardiac arrest successfully resuscitated and admitted to the ICU

Exclusion Criteria:

* trauma, drowning, electrocution, less than 18 years of age,

Where it's running

  • University medical center Maribor
    Maribor, Slovenia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.