Investigating MRI findings in children with Tourette syndrome
The Findings of Resting-state Functional Magnetic Resonance Imaging, Diffusion Spectrum Imaging, and Wideband Magnetic Resonance Imaging in Subtypes of Tics-related Disorders
This study is trying to see if brain scans can show differences in brain activity and connections in children with Tourette syndrome and chronic tics to better understand these conditions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 0 Years to 18 Years |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05566496 on ClinicalTrials.gov |
What this trial studies
This observational study examines the findings of resting-state functional magnetic resonance imaging (fMRI) and diffusion spectrum imaging in children diagnosed with Tourette syndrome and chronic tic disorders. The study aims to identify specific neuroimaging characteristics associated with different subtypes of tics-related disorders. By analyzing brain activity and connectivity patterns, researchers hope to enhance understanding of the neurological underpinnings of these conditions. The study will involve children under 18 years old who meet specific diagnostic criteria.
Who should consider this trial
Good fit: Ideal candidates for this study are children under 18 years old diagnosed with Tourette syndrome or chronic tic disorders.
Not a fit: Patients with a history of neuropsychiatric disorders or those currently receiving treatment for Tourette syndrome may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for children with Tourette syndrome.
How similar studies have performed: Other studies utilizing MRI to investigate neurological conditions have shown promising results, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age less than 18 years old * Diagnosed as Tourette syndrome or chronic tic disorders Exclusion Criteria: * History of neuropsychiatric disorders * Already receive treatment for Tourette syndrome/chronic tics disorder * Have some device not allowed for MRI scan
Where this trial is running
Taipei
- National Taiwan University Children Hospital Pediatric Neurology Department — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Wang-Tso Lee — National Taiwan University Children Hospital Pediatric neurology department
- Study coordinator: Wang-Tso Lee
- Email: leeped@hotmail.com
- Phone: (886)2-23123456
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.