Investigating MRI findings in children with Tourette syndrome
Official title: The Findings of Resting-state Functional Magnetic Resonance Imaging, Diffusion Spectrum Imaging, and Wideband Magnetic Resonance Imaging in Subtypes of Tics-related Disorders
Run by National Taiwan University Hospital · NCT05566496 · Data updated 2026-11-12
This study is trying to see if brain scans can show differences in brain activity and connections in children with Tourette syndrome and chronic tics to better understand these conditions.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 0 Years to 18 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | October 20, 2015 |
| Main results expected | August 1, 2025 |
| Study ends | December 2030 |
| Registry record updated | August 6, 2024 |
| Trial ID | NCT05566496 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are children under 18 years old diagnosed with Tourette syndrome or chronic tic disorders.
✕Probably not a fit
Patients with a history of neuropsychiatric disorders or those currently receiving treatment for Tourette syndrome may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines the findings of resting-state functional magnetic resonance imaging (fMRI) and diffusion spectrum imaging in children diagnosed with Tourette syndrome and chronic tic disorders. The study aims to identify specific neuroimaging characteristics associated with different subtypes of tics-related disorders. By analyzing brain activity and connectivity patterns, researchers hope to enhance understanding of the neurological underpinnings of these conditions. The study will involve children under 18 years old who meet specific diagnostic criteria.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for children with Tourette syndrome.
How similar studies have gone: Other studies utilizing MRI to investigate neurological conditions have shown promising results, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age less than 18 years old * Diagnosed as Tourette syndrome or chronic tic disorders Exclusion Criteria: * History of neuropsychiatric disorders * Already receive treatment for Tourette syndrome/chronic tics disorder * Have some device not allowed for MRI scan
Where it's running
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National Taiwan University Children Hospital Pediatric Neurology Department
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Wang-Tso Lee — National Taiwan University Children Hospital Pediatric neurology department
- Study coordinator: Wang-Tso Lee
- Email: leeped@hotmail.com
- Phone: (886)2-23123456
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Understanding premonitory urges during tic treatment with Habit Reversal Training
This study is testing how kids and teens with Tourette Disorder experience changes in their urges to tic while they try a treatment called Habit Reversal Training.
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Comparing Sertraline and Placebo for Treating Anxiety in Children with Neurodevelopmental Disorders
This study is testing if the medication sertraline can help reduce anxiety in children and teens aged 8-17 with neurodevelopmental disorders like autism and Fragile X syndrome compared to a placebo.
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Role of Neuroactive Steroids in Tourette Syndrome in Children
This study tests whether neuroactive steroids are linked to Tourette syndrome in kids and if they influence tic suppression and stress responses.
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Nature- and activity-based group programs for neurodivergent children and youth in Agder
This project will try outdoor and activity-based group programs to see if they help children and teens with ADHD, autism, Tourette's, and related neurodivergent challenges feel better, gain confidence, and do better in daily life.
-
Study of brain activity in patients with Tourette Syndrome
This study is testing how brain activity changes in adults with severe Tourette Syndrome who are getting deep brain stimulation to better understand their tics.
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Personalized deep brain stimulation for Tourette syndrome
This study is testing if personalized deep brain stimulation can help people with Tourette syndrome reduce their tics and improve related issues like anxiety and attention problems.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.