Investigating MPFL reconstruction outcomes in children

Medial Patellofemoral Ligament Reconstruction in Children - a 2-8 Years Follow-up Study

Observational Aarhus University Hospital · NCT06257836

This study looks at how well MPFL reconstruction surgery works for children with knee problems over several years compared to healthy kids.

Quick facts

Study typeObservational
Enrollment160 (estimated)
Ages14 Years to 23 Years
SexAll
SponsorAarhus University Hospital Academic / other
Locations1 site (Aarhus N)
Trial IDNCT06257836 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the long-term outcomes of medial patellofemoral ligament (MPFL) reconstruction in children suffering from chronic patellar instability. The study will involve a cohort of children who have undergone MPFL reconstruction using autologous tendon tissue and will compare their outcomes with a healthy control group matched by age and gender. The focus is on assessing the effectiveness of the surgical intervention over a follow-up period of 2 to 8 years. The study will also consider various factors that may influence the success of the reconstruction.

Who should consider this trial

Good fit: Ideal candidates for this study are children with chronic patellar instability who are undergoing MPFL reconstruction.

Not a fit: Patients who have had multiple surgeries on the same knee or a revision of MPFL in the index knee may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the effectiveness of MPFL reconstruction in improving knee stability and function in children.

How similar studies have performed: Other studies have shown promising results with MPFL reconstruction techniques, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria - Intervention group:

* MPFL-reconstruction with Quadriceps tendon graft
* Open physis at surgery date
* Minimum 2 years Follow up

Exclusion Criteria - Intervention group:

* More surgeries in index knee
* MPFL-r in opposite knee
* MPFL revision in index knee

Inclusion Criteria - Healthy group:

* No knee problems

Exclusion Criteria - Healthy group

* None
* No knee problems

Where this trial is running

Aarhus N

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Medial Patellofemoral DislocationMedial Patellofemoral Ligament ReconstructionMPFL, Knee, Medial Patellofemoral Ligament, Surgery
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.