Investigating melanoma in children, adolescents, and young adults

Novel Health Care Strategies for Melanoma in Children, Adolescents, and Young Adults. Histological, Computational, and Molecular Pathology for Improved Diagnosis. (Mol-Mel). Work Package 3 (WP3)

University of Florence · NCT06602648

This study is trying to learn more about melanoma in kids, teens, and young adults to help improve how it's diagnosed and treated.

Quick facts

Study typeObservational
Enrollment100 (estimated)
AgesN/A to 30 Years
SexAll
SponsorUniversity of Florence (other)
Locations1 site (Florence, Italy)
Trial IDNCT06602648 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore melanoma, a type of skin cancer, specifically in children, adolescents, and young adults, referred to as CAYA patients. Due to the rarity of melanoma in individuals under 30, the study seeks to gather critical information to improve diagnosis and treatment options for this demographic. It will involve standardization of tissue samples, histopathological analysis, and advanced imaging techniques to characterize melanoma samples. The data collected will also contribute to a Pan-European online platform for collaboration among healthcare professionals dealing with complex melanoma cases.

Who should consider this trial

Good fit: Ideal candidates include adolescents and young adults under 30 years with a histologically confirmed diagnosis of melanoma or related neoplasms.

Not a fit: Patients over 30 years of age or those without a confirmed diagnosis of melanoma will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for melanoma in young patients.

How similar studies have performed: While studies on melanoma exist, this specific focus on CAYA patients is relatively novel and underexplored.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adolescent and childhood patients (\< 20 years) or young adults (\< 30 years)
* histologically confirmed diagnosis of melanoma or intermediate/ambiguous melanocytic neoplasm (i.e., melanocytomas, SAMPUS, IAMPUS and MELTUMP according to WHO classification)

Exclusion criteria:

* adult patients (\> 30 years of age)
* patients without histologically confirmed diagnosis of melanoma or intermediate/ambiguous melanocytic neoplasm

Where this trial is running

Florence, Italy

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Melanoma of Skin, Melanoma, Pediatric, Childrens, Adolescents, Young adults

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.