Investigating markers in relapsing-remitting multiple sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore clinical, neurophysiological, and immunological markers in patients with relapsing-remitting multiple sclerosis (RRMS), including those receiving immunomodulatory treatment. It employs navigated transcranial magnetic stimulation (nTMS) to assess central nervous system function, alongside electromyoneurography (EMNG) for peripheral nervous system evaluation. Participants will undergo a series of neuropsychological assessments and blood tests to analyze immune markers. The findings may enhance understanding of MS pathophysiology and inform better diagnostic and treatment strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects with a documented diagnosis of relapsing-remitting MS according to the Mc Donald criteria (2005) and with EDSS achievement of 0-3.5 according to the modified Kurtzke's EDSS (Expanded disability status scale) for the assessment of neurological function and incapacity of patients with multiple sclerosis

Exclusion Criteria:

* Patients with metals in the body (e.g. pacemaker, dentures)
* Patients with new pregnancies (verbally confirmed)
* Patients with new head trauma
* Subjects unwilling to sign a consent or follow study procedures

Where it's running

• University of Split School of Medicine
  Split, Croatia Recruiting

Study contacts

• Principal investigator: Maja Rogić Vidaković, MSc, PhD — University of Split, School of Medicine
• Study coordinator: Maja Rogić Vidaković, MSc, PhD
• Email: maja.rogic@mefst.hr
• Phone: 0038598508210

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing Rituximab and Ocrelizumab for Relapsing-Remitting Multiple Sclerosis

  This study is testing whether rituximab can work just as well as ocrelizumab in helping people with relapsing-remitting multiple sclerosis manage their symptoms over two years.

  Recruiting at 9 sites Phase 3 Rennes University Hospital · Lyon, Bron and 22 other locations · NCT05758831

• Treadmill-based virtual reality walking training for MS patients

  This study tests whether a treadmill with virtual reality and smart socks can help people with multiple sclerosis walk better and feel safer in daily life.

  Recruiting Shepherd Center, Atlanta GA · Atlanta, Georgia · NCT07927439

• Virtual Reality and Mental Practice to Improve Balance and Walking in Relapsing MS

  This study tests whether virtual reality training or mental practice can improve balance and walking in people with relapsing–remitting multiple sclerosis.

  Recruiting Cairo University · Giza, Giza Governorate · NCT07918339

• REAL-MS: A Look at Autologous Stem Cell Transplant vs High-Efficacy MS Therapies in Real-World Care

  This study tests how AHSCT compares to high-efficacy MS medicines in adults treated in routine clinical care.

  Recruiting Imperial College London · London and 2 other locations · NCT07899502

• Tolebrutinib in real-world MS care for patients treated by clinicians

  This real-world study sees how tolebrutinib is used for multiple sclerosis patients and what outcomes look like in everyday practice.

  Recruiting Sanofi · Marina, Abu Dhabi Emirate · NCT07898371

• Pilates via live video vs. prerecorded videos for people with multiple sclerosis

  This study tests whether live, coach-led Pilates sessions through video calls are more beneficial than prerecorded Pilates videos for adults with MS.

  Recruiting Yuzuncu Yil University · Van · NCT07893925

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.