Investigating long-term vascular complications after radiation in head and neck cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the prevalence of cervical-cranial vascular complications in patients with head and neck cancer who have received radiation therapy. It will compare outcomes between patients with nasopharyngeal cancer and those with other types of head and neck cancers. Participants will be recruited based on their history of radiation treatment and will undergo brain imaging and vascular studies to evaluate complications. The study focuses on both early and long-term effects of radiation therapy on vascular health.

Why it matters

Who can join: the full rules

Population: Prospective cohort

Inclusion Criteria:

1. Age ≥20 years.
2. Head and neck cancer patient .
3. Had ever received radiation therapy (RT) ≦ 72 months before inclusion in the registry.
4. Had ≥ 1 brain images and cervical-cranial vascular studies between the end of RT and d date of enrolment.

Exclusion Criteria:

1. Age \<20 years.
2. Patients not willing to sign the informed consent.

Population: Retrospective validation cohort

Inclusion Criteria:

1. Age ≥20 years.
2. Head and neck cancer patient.
3. Had ever received radiation therapy (RT) \> 120 months before the adoption date of IRB at the participant site.
4. Had ≥ 2 brain images and cervical-cranial vascular studies between the end of RT and 6\~10 years after RT, one within 5 years after RT, the other after 5 years after RT.

Exclusion Criteria:

1.Age \<20 years.

Where it's running

• Chang Gung Memorial Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Chi-Hung Liu
• Email: ivanliu001@cgmh.org.tw
• Phone: (03)3281200

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.