Investigating long-term effects of sepsis in critically ill children

The Impact of Sepsis on Long-term Outcomes in Critical Ill Children With Sepsis

Observational West China Hospital · NCT06323226

This study looks at how sepsis affects critically ill children over five years to see how it impacts their growth, brain development, survival, and quality of life after leaving the hospital.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages0 Years to 16 Years
SexAll
SponsorWest China Hospital Academic / other
Locations1 site (Chengdu, Sichuan)
Trial IDNCT06323226 on ClinicalTrials.gov

What this trial studies

This observational study focuses on critically ill children who have experienced sepsis, tracking their long-term outcomes over a five-year period. The research aims to assess various factors such as growth, neurodevelopment, survival rates, and quality of life following their discharge from pediatric intensive care units. A control group of matched children without underlying diseases will also be included for comparison. The study seeks to provide insights into the lasting impacts of sepsis on young patients.

Who should consider this trial

Good fit: Ideal candidates are critically ill children under 16 years old who have been discharged from pediatric intensive care units after experiencing sepsis.

Not a fit: Patients with underlying diseases, cancer, or hematologic malignancies will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of the long-term effects of sepsis in children, leading to improved care and support strategies.

How similar studies have performed: While there have been studies on sepsis outcomes, this specific long-term observational approach in critically ill children is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

We included critically ill children with sepsis who successfully discharged from pediatric Intensive care units, age \< 16 years.

We also included age, sex, illness severity matched critically ill children as control group.

Exclusion Criteria:

We excluded children with underlying diseases, cancer, hematologic malignancy.

Where this trial is running

Chengdu, Sichuan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SepsisChildren, Only
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.