Investigating long-term effects of allergen immunotherapy in children
Long Term Effect of AIT in Children
This study is testing the long-term effects of allergy treatments in children aged 5 to 18 to see how well they work and if there are any ongoing allergy symptoms or asthma years after treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 4 Years to 18 Years |
| Sex | All |
| Sponsor | Odense University Hospital Academic / other |
| Drugs / interventions | immunotherapy |
| Locations | 2 sites (Odense, Odense C and 1 other locations) |
| Trial ID | NCT06421415 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the long-term effects of allergen immunotherapy in children aged 5 to 18 years who are treated at Hans Christian Andersen Children's Hospital. Participants will undergo either subcutaneous or sublingual immunotherapy for allergies related to grass pollen, birch, house dust mites, or venom. Data will be collected from patient records, including symptoms, medication use, and test results, with follow-up questionnaires administered 5 and 10 years post-treatment to evaluate ongoing allergy symptoms and asthma. The study will systematically monitor treatment effects and adverse events annually during the treatment period.
Who should consider this trial
Good fit: Ideal candidates are children aged 5 to 18 years who are receiving allergen immunotherapy at the participating hospital.
Not a fit: Patients who have received less than 12 months of allergen immunotherapy will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term effectiveness of allergen immunotherapy, potentially improving treatment strategies for children with allergies.
How similar studies have performed: While similar studies have explored the effects of allergen immunotherapy, this specific long-term observational approach in children is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: treated with allergen immunotherapy at HCA Children'sHospital, Odense University Hospital - Exclusion Criteria: received less than 12 months of treatment with allergen immunotherapy \-
Where this trial is running
Odense, Odense C and 1 other locations
- Hans Christian Andersen Children's Hospital — Odense, Odense C, Denmark (Recruiting)
- Hans Christian Andersen Children's Hospital — Odense, Denmark (Recruiting)
Study contacts
- Principal investigator: Josefine Gradman, PhD — Odense University Hospital
- Study coordinator: Josefine Gradman, PhD
- Email: josefine.gradman@rsyd.dk
- Phone: 0045 29241375
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.