Investigating liver health in adults with Turner Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the prevalence of liver alterations in adult patients with Turner Syndrome (TS) by analyzing laboratory and imaging data. It will involve a retrospective cohort of patients monitored at the Endocrinology and Diabetes Prevention and Care unit in Bologna. The study will collect detailed medical histories, anthropometric measurements, and laboratory investigations to identify potential etiopathogenetic factors associated with hepatopathy in TS patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of Turner syndrome made by karyotype analysis on peripheral blood.
* Age 18 years or older
* Written informed consent obtained

Exclusion Criteria:

* TS patients on therapy with drugs responsible for significant liver enzyme alterations (liver function alteration, LFA).

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Italy Recruiting

Study contacts

• Principal investigator: Alessandra Gambineri, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
• Study coordinator: Alessandra Gambineri, MD
• Email: alessandra.gambineri@aosp.bo.it
• Phone: +390512144628

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Inpegsomatropin vs Givopegsomatropin for short stature in girls with Turner syndrome

  A 52-week, multicenter, randomized study tests whether Inpegsomatropin injections help prepubertal girls with Turner syndrome grow taller compared with a known treatment.

  Recruiting at 49 sites Phase 3 Xiamen Amoytop Biotech Co., Ltd. · Anyang and 50 other locations · NCT07614152

• Parental plans and pregnancy outcomes in 93 women with Turner syndrome

  This project describes parental plans and pregnancy outcomes for adult women with Turner syndrome treated at Strasbourg University Hospitals between 2009 and 2019.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07344012

• Once-weekly lonapegsomatropin versus daily somatropin for children and adolescents with short stature due to growth-hormone-sufficient conditions

  It will test whether a once-weekly injection of lonapegsomatropin helps children and teens with Turner syndrome, SHOX mutation, small-for-gestational-age, or idiopathic short stature grow as well as or better than daily somatropin.

  Recruiting at 56 sites Phase 3 Ascendis Pharma A/S · Phoenix, Arizona and 55 other locations · NCT07221851

• Bleeding patterns with sequential versus continuous progesterone in adolescents with Turner syndrome

  This study will test whether taking progesterone continuously or in a sequential (monthly) schedule changes bleeding patterns in adolescents with Turner syndrome who are on estrogen replacement therapy.

  Recruiting Phase 4 Children's Mercy Hospital Kansas City · Kansas City, Missouri · NCT06834594

• Exercise testing in girls with Turner Syndrome

  This study tests how well girls aged 8-18 with Turner Syndrome can exercise by measuring their heart and lung performance during a special exercise test.

  Recruiting University Hospital, Ghent · Ghent · NCT06780514

• Comparing oral and transdermal estrogen therapy in women with Turner syndrome

  This study is testing whether taking estrogen as a pill or through the skin is better for women with Turner syndrome in terms of their overall health and well-being.

  Recruiting Phase 4 University of Aarhus · Aarhus, Aarhus N · NCT06570460

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.