Investigating kidney cell regeneration in nephropathy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study explores the role of renal progenitor cells and polyploid tubular cells in the context of glomerular and tubular diseases, particularly nephropathy. It focuses on how these cells can potentially regenerate lost podocytes and respond to damage during acute kidney injury. By examining patients undergoing renal biopsy for various glomerular diseases and those with acute kidney injury, the study aims to understand the mechanisms behind kidney cell regeneration and their implications for chronic kidney disease progression.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with glomerular diseases undergoing renal biopsy (e.g., rapidly progressive glomerulonephritis, minimal change disease, focal segmental glomerulosclerosis, diabetic nephropathy, lupus nephritis, membranous nephropathy, IgA nephropathy, etc)
* Patients with AKI, regardless of the nature of the damage (septal, ischemic, toxic, or unknown).
* Signed informed consent form

Exclusion Criteria:

* Sample insufficient and/or unavailable

Where it's running

• Meyer Children's Hospital IRCCS
  Florence, Italy Recruiting

Study contacts

• Study coordinator: Paola Romagnani, MD
• Email: paola.romagnani@meyer.it
• Phone: 055 5662562

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.