Investigating iron overload and its effects on endocrine diseases
"Iron Overload and Endocrinological Diseases"
This study is trying to see how iron overload affects adults with certain blood disorders and if it leads to problems with hormones and overall health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 62 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Azienda Ospedaliero-Universitaria di Modena Academic / other |
| Locations | 1 site (Modena) |
| Trial ID | NCT06137079 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the prevalence of endocrinological diseases in adult patients suffering from iron overload due to β-thalassemia major or intermedia and hereditary hemochromatosis. It seeks to understand the impact of these conditions on patients' well-being and quality of life. The study will assess the relationship between iron overload and various endocrine disorders, considering how these may evolve with age. By identifying the spectrum of endocrinopathies associated with iron overload, the research hopes to shed light on the underlying mechanisms and improve patient care.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 65 with a confirmed diagnosis of β-thalassemia major or intermedia or hereditary hemochromatosis.
Not a fit: Patients outside the age range of 18 to 65 or those without a diagnosis of the specified conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the relationship between iron overload and endocrine disorders, leading to better management strategies for affected patients.
How similar studies have performed: While the specific approach of this study may be novel, previous research has indicated a connection between iron overload and endocrine disorders, suggesting potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Certain diagnosis of β-thalassemia major or intermedia * Certain diagnosis of Hereditary Hemochromatosis * Adult patients with an age between 18 and 65 years Exclusion Criteria: * Subjects with an age \< 18 and \> 65 years
Where this trial is running
Modena
- Unit of Endocrinology of Azienza Ospedaliero-Universitaria di Modena — Modena, Italy (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.