Investigating hyperventilation in patients with chronic low back pain

Hyperventilation in Patients With Chronic Low Back Pain

Not applicable Interventional Hasselt University · NCT04074798

This study is trying to see if breathing too fast is connected to chronic low back pain and how it might affect balance and overall well-being.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment90 (estimated)
Ages20 Years to 60 Years
SexAll
SponsorHasselt University Academic / other
Locations1 site (Hasselt)
Trial IDNCT04074798 on ClinicalTrials.gov

What this trial studies

This study aims to explore the relationship between chronic low back pain (LBP) and hyperventilation, focusing on how impaired postural control may be linked to these conditions. Researchers will assess patients with chronic primary LBP for signs of hyperventilation, using both objective measures of carbon dioxide levels and subjective symptom reporting. Additionally, the study will evaluate the role of psychosocial factors in this relationship. The findings could provide insights into the underlying mechanisms of LBP and inform potential therapeutic approaches.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals with chronic primary low back pain lasting more than 12 weeks.

Not a fit: Patients with conditions such as chronic obstructive lung disease, major psychiatric conditions, or those who have undergone spinal surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for patients suffering from chronic low back pain by addressing underlying hyperventilation issues.

How similar studies have performed: While the specific relationship between hyperventilation and chronic low back pain is not extensively studied, similar investigations into breathing patterns and pain management have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria Patients:

* Chronic primary low back pain (\>12 weeks) as diagnosed by a medical doctor

Inclusion Criteria Healthy controls:

* No low back pain

Exclusion Criteria:

* Insufficient understanding of Dutch language
* Previous spinal surgery
* Chronic Obstructive Lung Disease, Interstitial Lung Disease, pulmonary vascular disease, asthma except for exertional asthma
* Acute cardiovascular or gastrointestinal disorders
* Neuromuscular disease interfering with normal lower limb or trunk functioning
* Acute pain or secondary chronic pain
* Pregnant and lactating women
* Major psychiatric conditions
* Acute lower limb problems
* Vestibular disorders

Where this trial is running

Hasselt

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Low Back Pain, RecurrentHyperventilation Syndrome
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.