Investigating how pregnancy-related anxiety affects the placenta and birth outcomes
Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes (MOMS Placenta)
This study is testing how anxiety during pregnancy affects the placenta and baby’s health by comparing standard care with a support program for expecting mothers.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | University of the Incarnate Word Academic / other |
| Locations | 1 site (San Antonio, Texas) |
| Trial ID | NCT04993742 on ClinicalTrials.gov |
What this trial studies
This study explores the relationship between prenatal maternal anxiety and placental health, focusing on inflammatory and oxidative stress responses. It involves a longitudinal, randomized clinical trial design where participants receive either standard prenatal care or an intervention program called Mentors Offering Maternal Support (M-O-M-S™). Participants will complete psychosocial questionnaires at various stages of pregnancy, and blood samples will be collected to assess physiological changes. The goal is to understand how maternal anxiety impacts both placental function and infant outcomes.
Who should consider this trial
Good fit: Ideal candidates are active duty and DoD beneficiary pregnant women aged 18 or older who are receiving prenatal care at Brooke Army Medical Center.
Not a fit: Patients who are military dependent daughters or VA beneficiaries will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prenatal care strategies that reduce maternal anxiety and enhance birth outcomes.
How similar studies have performed: Other studies have shown promising results in addressing maternal anxiety and its effects on pregnancy, suggesting that this approach may yield beneficial insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All Active Duty and DoD beneficiary gravid women, * 18 years of age or older, * Receiving prenatal care at BAMC, * English speaking Exclusion Criteria: * Military dependent daughters * VA beneficiaries
Where this trial is running
San Antonio, Texas
- Joint Base San Antonio — San Antonio, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Karen L Weis, PhD — University of Kansas Medical Center
- Study coordinator: Karen L Weis, PhD
- Email: kweis2@kumc.edu
- Phone: 785-822-0420
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.