Investigating how pregnancy health affects children's development and behavior

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between various genetic and environmental factors during pregnancy and their impact on the cognitive development of offspring. Pregnant women aged 20-49 will be enrolled, and data will be collected through questionnaires, blood samples, and developmental screenings at various stages of their child's growth. The study will assess factors such as maternal nutrition, mental health, and exposure to environmental toxins, and how these may correlate with developmental disorders in children. The goal is to identify potential risk factors for conditions like ADHD and developmental delays.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Inclusion criteria for pregnant women: Aged 20\~49;
2. no cognitive impairment, able to complete the scale test;
3. Hamilton Depression Scale (HAMD questionnaire) is normal (HAMD score \<8 points) or mild to moderate positive (HAMD questionnaire score: 8\~35 points);
4. Participants are asked for their own written informed content for the study;

Exclusion Criteria:

1. Patients receiving anti-depression therapy during the first 6 months of gestation or during pregnancy;
2. Patients with severe depression with scores of no less than 35 points in the HAMD questionnaire;
3. Patients with other mental disorders;
4. Patients with neurological diseases;
5. Patients with cognitive dysfunction.

Where it's running

• Wanzhou Health Center for Women and Children
  Chongqing, Chongqing Municipality, China Recruiting
• The People's Hospital of Yubei District of Chongqing City
  Chongqing, Chongqing Municipality, China Not yet recruiting
• Chongqing First People's Hospital of Liangjiang New Area
  Chongqing, Chongqing Municipality, China Not yet recruiting
• The Central Hospital of Jiangjin District of Chongqing City
  Chongqing, Chongqing Municipality, China Not yet recruiting
• The Maternal and Child Health Hospital of Hainan Province
  Haikou, Hainan, China Not yet recruiting

Study contacts

• Principal investigator: Tanya Froehlich, MD,MS — Children's Hospital Medical Center, Cincinnati
• Study coordinator: Li Chen, MD
• Email: chenli2012@126.com
• Phone: (+86)136 7762 0103

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pregnant Women Living with HIV on Bictegravir/Emtricitabine/Tenofovir Alafenamide

  This study looks at how B/F/TAF is used in pregnant women with HIV and whether it helps maintain viral suppression from before conception through delivery.

  Recruiting Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida · Paris · NCT07921472

• Pelvic Floor Training and a Modified Lumbopelvic Belt for Symphysis Pubis Pain in Pregnancy

  This study tests whether pelvic floor muscle training plus a modified lumbopelvic belt can reduce pain and improve function for pregnant women with symphysis pubis pain.

  Recruiting Kahramanmaras Sutcu Imam University · Kahramanmaraş · NCT07919548

• Effective Communication in VBAC Counseling

  This study tests how clearly doctors and midwives explain VBAC options during prenatal visits and whether patients feel understood.

  Recruiting IRCCS San Raffaele · Milan, MI · NCT07919145

• Innovative Multidisciplinary and Virtual Care for IBD in Pregnancy

  This study tests a dedicated IBD pregnancy care model, including a new virtual approach, to see if it improves access and quality of care for pregnant people with Crohn's disease or ulcerative colitis.

  Recruiting at 5 sites Austin Health · Hobart and 6 other locations · NCT07916727

• Compare spinal-epidural versus general anesthesia for babies after cesarean delivery

  This trial tests whether the type of anesthesia used for cesarean delivery affects newborn hearing in babies.

  Recruiting Second Affiliated Hospital of Wenzhou Medical University · Wenzhou · NCT07852624

• Pregnant women weight-management support via an app and care model

  Aims to try a smartphone-based weight-management program plus professional support for pregnant women to see if it helps manage gestational weight and promote healthy behaviors.

  Recruiting Mackay Medical College · Taipei · NCT07814885

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.