Investigating how portal vein thrombosis affects liver transplantation outcomes
Official title: A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation
Run by Beijing Friendship Hospital · NCT06513780 · Data updated 2026-11-12
This study looks at how having portal vein thrombosis affects the success of liver transplants to help doctors understand the risks and outcomes better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 700 (estimated) |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | January 1, 2016 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | September 18, 2025 |
| Trial ID | NCT06513780 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 years or older who are recipients of liver transplantation.
✕Probably not a fit
Patients undergoing retransplantation, multi-organ transplantation, or those with portal vein tumor thrombus may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the correlation between portal vein thrombosis (PVT) and the prognosis of liver transplantation. Participants will be divided into two groups: those with PVT and those without, allowing for comparative analysis of their data. The study will estimate the prevalence and risk factors associated with PVT, develop a predictive model for clinical use, and assess the prognostic impact of PVT on liver transplantation outcomes. Data will be collected from various medical imaging, surgical procedures, and follow-up treatments.
Why it matters
Potential benefit: If successful, this study could improve the management and outcomes of liver transplantation for patients with portal vein thrombosis.
How similar studies have gone: While similar studies have explored aspects of portal vein thrombosis, this specific correlation with liver transplantation prognosis is less commonly investigated, making it a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Liver transplantation recipients 2. Aged 18 years or older. Exclusion Criteria: 1. Retransplantation 2. Multi-organ transplantation 3. Portal vein tumor thrombus
Where it's running
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Beijing Friendship Hospital, Capital Medical University
Beijing, China Recruiting
Study contacts
- Study coordinator: Ru-zhou Cai, M.D.
- Email: 18722563616@126.com
- Phone: 18722563616
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Apixaban plus carvedilol to prevent portal-hypertension complications in cirrhosis
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Apixaban for portal vein clots that appear more than a year after laparoscopic splenectomy
This trial tests whether taking apixaban twice daily can treat portal vein blood clots that develop more than a year after laparoscopic splenectomy in people with cirrhosis.
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Apixaban for portal vein thrombosis occurring more than one year after laparoscopic splenectomy and azygoportal disconnection
This trial will try whether taking apixaban 2.5 mg twice daily can treat portal vein clots that appear more than a year after laparoscopic splenectomy and azygoportal disconnection in people with cirrhosis.
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Comparing blood thinners for people with cirrhosis and portal vein clots
This will try enoxaparin, warfarin, or apixaban in people with cirrhosis and portal vein thrombosis (with or without liver cancer) to see which controls the clot and is safest.
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This study is collecting information from patients with serious portal hypertension who are getting a TIPS procedure to see how well it works and what complications might happen afterward.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.