Investigating how oral iron doses affect serum ferritin levels in iron-deficient women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the immediate effects of oral iron supplementation on serum ferritin levels in women with low iron stores but no anemia. Participants will receive either 80 mg or 160 mg of ferrous sulfate daily for two months to assess how these doses influence serum ferritin levels over time. The goal is to understand the acute changes in ferritin levels to improve monitoring of iron status during supplementation. The study focuses on women aged 18 to 45 with specific eligibility criteria to ensure accurate results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Low iron stores (SF levels \< 30 µg/L),
* no anemia (Hb \> 120 g/L)
* no inflammation (CRP \< 5 mg/L)
* 18 to 45 years old.
* Body weight \<70 kg
* Normal body Mass Index (18.5-26.5 kg/m2)

Exclusion Criteria:

* Any chronic or acute disease
* Consumption of mineral and vitamin supplements since screening and over the study period
* Blood transfusion, blood donation or significant blood loss over the past 4 months,
* Pregnant or breastfeeding,
* Continuous/long-term use of medication during the whole studies (except for contraceptives)
* Therapeutic iron infusion over the past 6 months,
* Known hypersensitivity or allergy to iron supplements,
* Intention to become pregnant over the course of the study

Where it's running

• Laboratory of Nutrition and Metabolic Epigenetics
  Zurich, Canton of Zurich, Switzerland Recruiting

Study contacts

• Study coordinator: Nicole Stoffel, PhD
• Email: nicole.stoffel@hest.ethz.ch
• Phone: +41 44 632 83 93

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• Donor Breast Milk with Early Iron Supplementation in Very Preterm Infants

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• Preconception versus early-pregnancy iron screening and treatment

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.