Investigating how monocytes affect blood cell growth in myeloproliferative neoplasia

Exploring the Impact of Monocytes in Myeloproliferative Neoplasia

University Hospital, Brest · NCT06462664

This study is trying to see how certain immune cells called monocytes affect the growth of blood cells in people with myeloproliferative neoplasia.

Quick facts

Study typeObservational
Enrollment10 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Brest (other)
Locations1 site (Brest)
Trial IDNCT06462664 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the role of monocytes in the growth and differentiation of hematopoietic stem cells in patients diagnosed with myeloproliferative neoplasia (MPN). By examining these cellular interactions in vitro, the study seeks to provide insights into the underlying mechanisms of MPN. Participants will be recruited from a single center, and their monocyte activity will be analyzed to understand its impact on disease progression.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old who have been diagnosed with myeloproliferative neoplasia.

Not a fit: Patients who are unable to provide consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to new therapeutic strategies targeting monocyte activity in patients with myeloproliferative neoplasia.

How similar studies have performed: While this specific approach is novel, similar studies exploring cellular interactions in hematological conditions have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of MPN in the participating center
* Over 18 yo

Exclusion Criteria:

* Not able to consent

Where this trial is running

Brest

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Myeloproliferative Neoplasm

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.