Investigating how lipoproteins affect platelet function in healthy individuals and those with lipid disorders
Official title: Lipoprotein Functions in Healthy Individuals and Subjects With Lipid Disorders
Run by The Miriam Hospital · NCT06747000 · Data updated 2026-11-12
This study looks at how certain fats in the blood affect blood cell function in both healthy people and those with cholesterol issues to help understand heart disease better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 69 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | The Miriam Hospital Academic / other |
| Locations | 2 sites (East Providence, Rhode Island and 1 other locations) |
| Status | Recruiting |
| Started | July 18, 2024 |
| Main results expected | July 18, 2028 |
| Study ends | July 18, 2029 |
| Registry record updated | October 1, 2025 |
| Trial ID | NCT06747000 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include healthy individuals and those aged 18 to 69 with abnormalities in lipid panels.
✕Probably not a fit
Patients with drug or alcohol abuse issues, significant mental impairments, current smokers, or known bleeding disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines the role of lipoproteins in influencing heart and blood vessel health, particularly in individuals with lipid disorders. It focuses on understanding how the functionality of these lipoproteins, rather than just their levels, impacts cardiovascular risk. By analyzing structural and functional changes in lipoproteins and their effects on platelet activity, the study aims to uncover new insights into the prevention and treatment of heart disease. Participants will include both healthy volunteers and those with abnormalities in lipid panels.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for preventing and treating heart disease by enhancing our understanding of lipoprotein functionality.
How similar studies have gone: While the study explores a novel approach to understanding lipoprotein functionality, similar studies have indicated the importance of lipoproteins in cardiovascular health, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy volunteers * Abnormalities in lipid panels * Able to provide informed consent * Between the age of 18 and 69 Exclusion Criteria: * Drug or alcohol abuse within 6 months or significant mental/psychological impairment * Current smokers * Subjects with known bleeding disorders (for example, hemophilia) * Subjects requiring regular transfusions for any reason * No ethnic/racial groups will be excluded
Where it's running
-
Brown University Health Lipid Clinic
East Providence, Rhode Island, United States Recruiting -
Cardiovascular Research Center
Providence, Rhode Island, United States Recruiting
Study contacts
- Study coordinator: Wenliang Song, MD
- Email: WSong@brownhealth.org
- Phone: 4014449851
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.