Investigating how lean beef affects heart health and gut bacteria
Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome
NA · University of Missouri-Columbia · NCT06433115
This study is testing how eating lean beef compared to plant-based meat affects heart health and gut bacteria in people over six weeks.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | University of Missouri-Columbia (other) |
| Locations | 1 site (Columbia, Missouri) |
| Trial ID | NCT06433115 on ClinicalTrials.gov |
What this trial studies
This study examines the impact of consuming lean beef on cardiometabolic health and the gut microbiome over a 6-week period. Participants will be randomly assigned to one of three diets: lean grain-fed beef, lean grass-fed beef, or plant-based meat. The trial aims to assess various metabolic, inflammatory, and gut microbiome markers to determine the health effects of these dietary interventions.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 18-45 with a BMI between 18-35 who are willing to follow the study diet.
Not a fit: Patients with diabetes, gastrointestinal diseases, or those on specific medications affecting metabolism may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into dietary recommendations that improve heart health and gut microbiome balance.
How similar studies have performed: While there have been studies on diet and gut health, this specific approach comparing different types of beef and plant-based meat is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: 18-45 years of age * BMI: 18-35 kg/m2 * Willingness to consume study foods. * Willing to comply with study protocol. * Consistent diet and activity patterns for 4 weeks * Weight stable (≤5 kg change over the last 3 months) * Non-smoker \>1 year or more Exclusion Criteria: * Allergies to foods provided in the study * Diabetes * Gastrointestinal disease and/or bariatric surgery * Uncontrolled hypertension and blood pressure ≥ 180/110 * Illicit drug use * Recent consumption of antibiotics or probiotics * Recent start of medications that affect metabolism or appetite. * Recent blood donation * Drug therapy for coronary artery disease, peripheral artery disease, congestive - heart failure, or dyslipidemia * Pregnant or lactating individuals * Taste or smell disorders * High consumers of red meat or plant-based meat (≥ 4 times/week)
Where this trial is running
Columbia, Missouri
- University of Missouri-Columbia — Columbia, Missouri, United States (RECRUITING)
Study contacts
- Principal investigator: Jaapna Dhillon, PhD — University of Missouri-Columbia
- Study coordinator: Jaapna Dhillon
- Email: jdhillon@missouri.edu
- Phone: 573-884-2103
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Diet Intervention