Investigating how COVID-19 affects patients with hyperthyroidism
Effect of COVID-19 Infection on Thyroid Function and Psychological Status in Patients With Hyperthyroidism-one-year Intervention and Follow-up
This study looks at how COVID-19 affects people with hyperthyroidism, especially those with Graves disease, to see if their symptoms, anxiety, and depression change before and after getting the virus.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Qilu Hospital of Shandong University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT06204393 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between COVID-19 and hyperthyroidism in patients diagnosed with Graves disease. It will assess changes in hyperthyroidism symptoms, anxiety, and depression before and after COVID-19 infection, as well as the impact of psychological interventions. Participants will undergo regular follow-ups for one year, during which their thyroid function and related health indicators will be monitored. The study seeks to provide insights into the complications faced by hyperthyroid patients during and after COVID-19.
Who should consider this trial
Good fit: Ideal candidates are patients diagnosed with hyperthyroidism, specifically Graves disease, who have also contracted COVID-19.
Not a fit: Patients with severe autoimmune diseases, hematological diseases, or those with incomplete data may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for hyperthyroid patients affected by COVID-19.
How similar studies have performed: While the specific correlation between COVID-19 and hyperthyroidism is still being explored, other studies have shown that viral infections can impact thyroid function, suggesting potential relevance.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. According to the diagnostic criteria of hyperthyroidism in the Chinese Guidelines for the Diagnosis and Treatment of Thyroid Diseases formulated by the Chinese Society of Endocrinology of the Chinese Medical Association, the patient had been diagnosed with hyperthyroidism. 2. In accordance with the diagnostic criteria of "The diagnosis and Treatment Protocol for novel coronavirus Infection (Trial version 10). Exclusion Criteria: 1. Cases with incomplete data 2. Patients with severe autoimmune diseases, hematological diseases and malignant tumors 3. Immunodeficiency (e.g.AIDS, long-term use of corticosteroids or other immunosuppressive drugs leading to immunodeficiency) 4. Follow-up was less than 30 days 5. The results of thyroid function were less than 3 times
Where this trial is running
Jinan, Shandong
- Qilu Hospital of Shandong University — Jinan, Shandong, China (Recruiting)
Study contacts
- Principal investigator: Kuanxiao Tang, M.D. — Qilu Hospital of Shandong University
- Study coordinator: Kuanxiao Tang, M.D.
- Email: tangkx_ql@hotmail.com
- Phone: 18560082261
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.