Investigating how chronic e-cigarette use affects microvascular health
The Impact of Chronic E-Cigarette Usage on Microvascular Health
Virginia Commonwealth University · NCT06860698
This study is testing how long-term e-cigarette use affects the small blood vessels in young adults aged 18 to 29 compared to those who don’t use e-cigarettes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 44 (estimated) |
| Ages | 18 Years to 29 Years |
| Sex | All |
| Sponsor | Virginia Commonwealth University (other) |
| Locations | 1 site (Richmond, Virginia) |
| Trial ID | NCT06860698 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the impact of chronic e-cigarette usage on microvascular health among young adults aged 18 to 29. Participants who regularly use e-cigarettes will be compared to non-users to assess differences in health outcomes related to microvascular function. Various techniques, including iontophoresis, will be employed to evaluate the physiological effects of e-cigarette consumption. The study seeks to fill gaps in understanding the health implications of e-cigarettes, which are often marketed as safer alternatives to traditional smoking.
Who should consider this trial
Good fit: Ideal candidates for this study are young adults aged 18 to 29 who have been using e-cigarettes with nicotine at least three times a week for the past six months.
Not a fit: Patients who are older than 29, former smokers, or have significant health issues related to cardiovascular or pulmonary health may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the health risks associated with e-cigarette use, potentially guiding public health recommendations.
How similar studies have performed: While there is ongoing research into the effects of e-cigarettes, this specific focus on microvascular health is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
e-Cig users arm Inclusion Criteria: * Between 18 and 29 years of age * Used e-cigarettes with nicotine (≥3 times/week for ≥6 months) Exclusion Criteria: * 17 years old and younger or 30 years old or older. * Former combustible tobacco user/ former smoker * Use of cigarettes for 15 days or more in the past 60 days * Use of other tobacco products (cigars, hookah, smokeless), marijuana and/or illicit or prescription drugs weekly or more frequently in the past 60 days * Evidence of cardiovascular, pulmonary, renal, hepatic, metabolic, cerebral diseases or sleep disorders * Disorder or use of medication that affects cardiopulmonary health * Evidence of pregnancy or current nursing Non e-Cig using arm Inclusion \- Between 18 and 29 years of age Exclusion * 17 years old and younger or 30 years old and older * Use of cigarettes or other tobacco products more than 50 times in their lifetime. * Evidence of cardiovascular, pulmonary, renal, hepatic, metabolic, cerebral diseases or sleep disorders * Disorder or use of medication that affects cardiopulmonary health * Evidence of pregnancy or current nursing
Where this trial is running
Richmond, Virginia
- Virginia Commonwealth University — Richmond, Virginia, United States (RECRUITING)
Study contacts
- Principal investigator: Paula Rodriguez Miguelez — Virginia Commonwealth University
- Study coordinator: Paula Rodriguez Miguelez
- Email: prodriguezmig@vcu.edu
- Phone: (804) 396-4498
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: E-Cig Use, Microvascular Health