Investigating how carbon dioxide levels affect eye pressure in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the relationship between arterial carbon dioxide concentration and vitreous pressure on choroidal volume in children undergoing eye exams under anesthesia. Using integrated intraoperative OCT imaging, the thickness of the choroid will be measured while manipulating end-tidal CO2 levels. The goal is to understand how changes in CO2 levels may influence intraocular pressure and potentially lead to complications during eye procedures. Children aged newborn to 8 years with normal eyes will be included, and various measurements will be taken to ensure accuracy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* any child undergoing an eye exam under anesthesia for an ophthalmologic reason.
* children between the ages newborn to 8 years of age.

Exclusion Criteria:

* children who are not having an eye exam under anesthesia.
* children with a known medical diagnosis that affect the eye to be studied
* \* children over the age of 8 years of age.
* \* children with altered cerebral autoregulation, increased intracranial pressure, pulmonary hypertension, or any other condition deemed appropriate by the anesthesiologist.
* children in whom a laryngeal mask airway will not be used

Where it's running

• University of Pittsburgh Medical Center
  Pittsburgh, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Kanwal Nischal, MD,FRCOphth — University of Pittsburgh
• Study coordinator: Amy Monroe, MPH, MBA
• Email: monroeal@upmc.edu
• Phone: 412-623-6382

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.