Investigating how canola protein processing affects amino acid responses in the blood
The Impact of Canola Protein Processing on Postprandial Plasma Amino Acid Responses in Vivo in Young Females
This study tests how different ways of processing canola protein affect amino acid levels in the blood of healthy women aged 18 to 35.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | Female |
| Sponsor | Maastricht University Medical Center Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Maastricht, Limburg) |
| Trial ID | NCT06058403 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effects of different processing methods of canola protein on plasma amino acid responses in healthy female participants aged 18 to 35. Participants will undergo a screening process to assess eligibility based on health criteria and will then consume various protein drinks, including whey and different forms of processed canola protein. The study will standardize test days according to the menstrual cycle to account for hormonal influences on protein metabolism. Blood samples will be taken to measure amino acid levels after ingestion of the protein drinks.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy females aged 18 to 35 with a BMI between 18.5 and 30 kg/m2.
Not a fit: Patients who are lactose intolerant, allergic to milk proteins, or following a vegan lifestyle may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of plant protein digestion and improve dietary recommendations for individuals with protein metabolism disorders.
How similar studies have performed: While studies on protein digestion exist, this specific investigation into canola protein processing is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female sex * Aged between 18 and 35 y inclusive * BMI between 18.5 and 30 kg/m2 Exclusion Criteria: * Intolerant to milk lactose * Allergic to milk protein / products * Mustard allergy * Vegan lifestyle * Participating in a structured (progressive) exercise program * Smoking regularly * Diagnosed GI tract disorders or diseases * Diagnosed musculoskeletal disorders * Diagnosed metabolic disorders (e.g., diabetes) * Hypertension (blood pressure above 140/90 mmHg) * Donated blood 2 months prior to test day * Pregnant * Using third generation oral contraceptives * Use of any medications known to affect protein metabolism (i.e., corticosteroids, non-steroidal anti-inflammatories). * Chronic use of gastric acid suppressing medication as this impairs protein digestion (i.e., proton pump inhibitors, H2-antagonists) * People with Phenylketonuria
Where this trial is running
Maastricht, Limburg
- Maastricht University Medical Centre+ — Maastricht, Limburg, Netherlands (Recruiting)
Study contacts
- Principal investigator: Luc van Loon, PhD — Maastricht University
- Study coordinator: Wesley Hermans, MSc
- Email: w.hermans@maastrichtuniversity.nl
- Phone: 0031433881810
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.