Investigating how brain activity affects arm movement during walking after stroke
The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke.
This study tests how brain activity affects arm movement while walking in people who have had a stroke compared to healthy individuals.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | University Hospital, Ghent Academic / other |
| Locations | 1 site (Ghent, Oost-Vlaanderen) |
| Trial ID | NCT06442579 on ClinicalTrials.gov |
What this trial studies
This study examines the role of upper limb motor control in walking for individuals who have experienced a stroke. It aims to understand how cortical activity influences arm swing during independent walking by comparing post-stroke patients with healthy controls. The research will evaluate muscle synergies and analyze EEG data to assess the relationship between cortical changes and arm swing deviations. Participants will engage in treadmill walking to gather data on their motor control capabilities.
Who should consider this trial
Good fit: Ideal candidates include individuals who have had a first-ever ischemic stroke within the past year and have upper limb paresis.
Not a fit: Patients with other neurological disorders or those who are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation strategies for stroke patients, enhancing their walking ability and overall quality of life.
How similar studies have performed: While the specific focus on cortical lateralization and arm swing during walking is novel, related studies have shown promise in understanding motor control post-stroke.
Eligibility criteria
Show full inclusion / exclusion criteria
Stroke Inclusion Criteria: * First-ever and cerebral stroke * Able to walk at least 10 minutes (FAC ≥ 3) * Presence of upper limb paresis (NIHSS item 5a/b \> 0) Exclusion Criteria: * Other neurological disorders Healthy controls Inclusion criteria: * Older than 18 years * Able to walk at least 10 minutes Exlusion criteria: * Pregnancy
Where this trial is running
Ghent, Oost-Vlaanderen
- Ghent University Hospital — Ghent, Oost-Vlaanderen, Belgium (Recruiting)
Study contacts
- Principal investigator: Anke Van Bladel, PhD — Ghent University and Ghent University Hospital
- Study coordinator: Arne Defour, Msc.
- Email: Arne.Defour@UGent.be
- Phone: 09 332 12 43
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.