Investigating how amino acids affect muscle growth with beta2-adrenergic stimulation.
Official title: The Importance of Amino Acid Availability in Modulating the Muscle Anabolic Response to β2-adrenergic Stimulation.
Run by University of Copenhagen · NCT06654986 · Data updated 2026-11-12
This study is testing how different amino acids can help young, fit people build muscle when combined with a specific medication that stimulates muscle growth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | University of Copenhagen Academic / other |
| Locations | 1 site (Copenhagen) |
| Status | Recruiting |
| Started | October 31, 2024 |
| Main results expected | December 18, 2026 |
| Study ends | December 18, 2026 |
| Registry record updated | April 9, 2025 |
| Trial ID | NCT06654986 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy, physically active men and women aged 18-40 with high aerobic fitness levels.
✕Probably not a fit
Patients who are smokers, have chronic illnesses, or are outside the age range may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to explore the impact of amino acid availability on the muscle anabolic response when stimulated by beta2-adrenergic agents in young, healthy individuals. Participants will be administered either Salmeterol combined with amino acids, Salmeterol with a placebo, or a placebo with a placebo to assess the differences in muscle growth response. The study focuses on physically active men and women aged 18-40 who have a high level of aerobic fitness. By analyzing the effects of these interventions, the research seeks to provide insights into optimizing muscle hypertrophy.
Why it matters
Potential benefit: If successful, this study could enhance strategies for muscle growth and recovery in physically active individuals.
How similar studies have gone: While the specific combination of beta2-adrenergic stimulation and amino acid availability is novel, similar studies have shown promising results in muscle hypertrophy research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-40 * Physically active \>5 hours a week * Maximum oxygen uptake classified as high or very high Exclusion Criteria: * Active smoker currently or within the past 5 years * Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women) * Chronic or acute illness deemed by the responsible study physician to affect the test parameters * Deviation from the study protocol * Lean mass index \>21 kg/m² * Pregnancy * Smoker * Blood donation during the past 3 months
Where it's running
-
August Krogh Building
Copenhagen, Denmark Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.