Investigating heart rate variability in people with chronic neck pain
Autonomic Nervous System Dysregulation in People With Chronic Neck Pain - Indicated by Heart Rate Variability
This study is testing how heart rate changes in people with chronic neck pain compared to healthy individuals when they are in different positions and under physical stress.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 56 (estimated) |
| Ages | 20 Years to 59 Years |
| Sex | All |
| Sponsor | National Yang Ming Chiao Tung University Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT06554704 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore heart rate variability (HRV) in individuals with non-specific chronic neck pain compared to healthy controls. It will assess HRV in different body positions and during an isometric hand-grip test to understand how the autonomic nervous system responds to physical stress. The study will involve 28 participants with chronic neck pain and 28 age- and gender-matched healthy controls, measuring HRV through electrocardiography in various conditions. The findings may provide insights into the physiological responses associated with chronic neck pain.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 20-59 with non-specific chronic neck pain persisting for over 90 days.
Not a fit: Patients with neurological diseases, orthopedic disorders, or those on medications affecting physical activity or pain perception may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of autonomic nervous system dysregulation in chronic neck pain, potentially leading to improved treatment strategies.
How similar studies have performed: While there is limited research on autonomic nervous system dysregulation in chronic neck pain, similar studies have shown promising results in related areas.
Eligibility criteria
Show full inclusion / exclusion criteria
Chronic neck pain inclusion criteria: * Chronic pain (persistent or recurrent pain \>90 days) * Non-specific chronic neck pain and non-irradiated to the upper limbs (Superior nuchal line \~ scapular spine \~ acromion) Chronic neck pain \& healthy control inclusion criteria: * Age- and gender- matched (age: 20\~59 y/o) * BMI between 18.5\~24.9 (Normal weight) * Work at least 75% of full-time work Exclusion criteria: * Neurological diseases * Orthopedic disorders * Other disorders or regular use of medications known to affect physical activity, autonomic nervous system or pain perception
Where this trial is running
Taipei
- National Yang-Ming University, Taiwan, R.O.C. — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Ray-Yau Wang — National Yang Ming Chiao Tung University
- Study coordinator: Ray-Yau Wang
- Email: rywang@nycu.edu.tw
- Phone: +88628267210
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.