Investigating heart changes in young patients with atrial fibrillation

Progression of Atrial Fibrillation in the Young

Observational Karolinska Institutet · NCT05080712

This study looks at how the hearts of young people with atrial fibrillation change over time to see if these changes affect their health.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorKarolinska Institutet Academic / other
Locations1 site (Stockholm)
Trial IDNCT05080712 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the structural changes in the hearts of young patients diagnosed with atrial fibrillation (AF) and how these changes develop over time. It includes 100 patients who will undergo comprehensive assessments, including echocardiographic measurements and blood tests, to evaluate their heart function and biomarkers. Participants will be monitored for five years with annual follow-ups involving continuous ECG recordings and clinical assessments to track their symptoms and treatment outcomes.

Who should consider this trial

Good fit: Ideal candidates are young individuals diagnosed with symptomatic atrial fibrillation within the past year.

Not a fit: Patients with atrial fibrillation lasting over one year or those with acute stressors like infections or ischemic heart disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of atrial fibrillation progression in young patients, leading to better management strategies.

How similar studies have performed: While there have been studies on atrial fibrillation, this specific focus on young patients and long-term structural changes is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Atrial fibrillation
* Diagnosis of atrial fibrillation within one year of inclusion

Exclusion Criteria:

* Duration of atrial fibrillation over one year.
* Acute stressor for atrial fibrillation such as: acute ischemic heart disease or infection

Where this trial is running

Stockholm

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Atrial Fibrillationatrial fibrillationprogressionleft atrial function
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.