Investigating genetic variants in psychiatric disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on analyzing genetic variants found in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, autism spectrum disorder, and resistant depression. It aims to investigate how these genetic variants are inherited within families and to explore their functional consequences in the cells of patients and their relatives. The study will enrich biocollections with DNA samples from blood or saliva, as well as hair follicles from participants, to facilitate further genetic analysis. Participants must be over 18 years old and affiliated with the social security system.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* For patients:
* Subjects suffering from (according to DSM IV criteria) : Bipolar disorder, Unipolar depression, Schizophrenia, Autism spectrum disorder
* Age over 18 years
* Subject affiliated to the social security system
* Including patients under guardianship, curatorship,
* Patients included in the Fondation FondaMental cohort whose genetic analyses have revealed the need for comparative and functional genetic studies.
* Having signed the consent form

For relatives :

* Age over 18 years
* Relative of patient included in the Fondattion FondaMental cohort
* Including relative under guardianship, curatorship
* Having signed the consent
* Affiliated to social security

Exclusion Criteria:

* For all subjects:
* Any condition that, in the opinion of the investigator, would make the subject's participation in the study undesirable or that would compromise compliance with the protocol
* Persons deprived of liberty
* Inability to understand French

Where it's running

• Hopital Albert Chenevier
  Créteil, France Recruiting

Study contacts

• Study coordinator: Stephane JAMAIN, PhD
• Email: stephane.jamain@inserm.fr
• Phone: 149813775

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.