Investigating genetic factors in Takotsubo cardiomyopathy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore whether there is a genetic predisposition that makes certain individuals more susceptible to acute stress-induced (takotsubo) cardiomyopathy, also known as broken heart syndrome. The researchers will collect blood samples from patients diagnosed with this condition in Scotland since 2010 and conduct a genome-wide association study to identify potential genetic variants. By understanding the genetic and epidemiologic factors associated with this disorder, the study seeks to advance knowledge in this area and potentially benefit affected families.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients who have been diagnosed with Takotsubo cardiomyopathy in Scotland between 2010 to date.
* Familial cases elsewhere in the world who would be willing to participate.

Exclusion Criteria:

* Unwillingness to participate

Where it's running

• Cardiac Research Office, Aberdeen Royal Infirmary
  Aberdeen, Aberdeenshire, United Kingdom Recruiting
• Cardiovascular Research Facility
  Aberdeen, Aberdeenshire, United Kingdom Recruiting

Study contacts

• Principal investigator: Dana K Dawson, MD, MPhil — University of Aberdeen
• Study coordinator: Amelia E Rudd, MSc
• Email: a.e.rudd@abdn.ac.uk
• Phone: 01224559473

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Manganese MRI to image heart changes after takotsubo (broken heart) cardiomyopathy

  This project will test whether manganese-enhanced cardiac MRI, together with common heart medications, can reveal ongoing heart muscle changes in adults with takotsubo (broken heart) cardiomyopathy.

  Recruiting University of Edinburgh · Edinburgh · NCT07491718

• Investigating heart issues in COPD patients during hospital stays

  This study is trying to see if sudden worsening of COPD can cause heart problems in hospitalized patients and how it affects their recovery.

  Recruiting Sahlgrenska University Hospital · Gothenburg, Region Västra Götaland · NCT06597331

• Resilience training for patients with heart disease

  This study tests a resilience training program to see if it helps heart disease patients cope better with stress and improve their overall quality of life.

  Recruiting Pensionsversicherungsanstalt · Bad Tatzmannsdorf, Burgenland · NCT06332859

• Using cardiac imaging to improve risk assessment in Takotsubo syndrome

  This study is testing a new way to predict how well patients with Takotsubo syndrome will do in the hospital and over time by using heart imaging and comparing it to current methods.

  Recruiting University of Cagliari · Cagliari, Italy · NCT06277297

• Virtual support group for patients with Takotsubo syndrome

  This study is testing if joining a virtual support group can help adults with Takotsubo syndrome feel less anxious after a year.

  Recruiting Weill Medical College of Cornell University · New York, New York · NCT05977049

• Using Cyclosporine to treat Takotsubo Syndrome

  This study is testing if a medication called Cyclosporine can help people with Takotsubo syndrome recover better and have less heart damage compared to those who get a placebo.

  Recruiting at 24 sites Phase 2 University Hospital Heidelberg · Bad Nauheim and 23 other locations · NCT05946772

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.