Investigating genetic factors in patients with neurodegenerative dementia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the genetic status of patients presenting with neurodegenerative dementias such as Alzheimer's disease, Frontotemporal dementia, and Lewy Body dementia. By collecting biosamples from individuals with suspected or confirmed diagnoses, as well as their biological family members, the study seeks to identify specific genetic mutations or polymorphisms associated with these conditions. The research focuses on understanding the genetic contributions to these diseases, which remain largely unknown. Participants must be 18 years or older and consent to a blood draw for genetic analysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Persons presenting to the cognitive clinic with a neurodegenerative disorder (for example, AD, FTD, LBD, ALSP, and related conditions);
* Biological family members of someone diagnosed with a neurodegenerative disorder, presenting to clinic;
* Age 18+ years old;
* Consenting to a blood draw.

Exclusion Criteria:

• Persons declining / unwilling / not able to have a blood draw.

Where it's running

• Parkwood Institute
  London, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Elizabeth Finger, MD — London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
• Study coordinator: Sarah Jesso
• Email: cognitiveneurology@sjhc.london.on.ca
• Phone: 519-646-6000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.