Investigating gallbladder stones in children and their causes
Histochemical Analysis of Gallbladder Stones in Children and Correlation With Etiological Factors
NA · Sohag University · NCT06660576
This study is trying to find out what causes gallbladder stones in children by looking at their stones after surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Sohag University (other) |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06660576 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the relationship between various etiological factors and the histochemical characteristics of gallbladder stones in pediatric patients. It will be conducted as a prospective cohort study at Sohag University Hospital, running from October 2024 to August 2025. Eligible participants include children under 18 years with symptomatic gallbladder stones or specific asymptomatic cases, while those over 18 or with certain biliary anomalies will be excluded. The primary intervention involves cholecystectomy followed by histochemical analysis of the stones.
Who should consider this trial
Good fit: Ideal candidates are children under 18 years with symptomatic gallbladder stones or specific asymptomatic cases.
Not a fit: Patients over 18 years or those with certain biliary anomalies will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of gallbladder stones in children, potentially leading to improved treatment strategies.
How similar studies have performed: While there may be studies on gallbladder stones in adults, this specific focus on pediatric cases and their etiological factors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion criteria: Age \<18 years . Symptomatic gallbladder stones (biliary colic, fever, vomiting, positive Murphy sign ) . Congenital hemolytic anemia with gallbladder stones. Asymptomatic patient with gallbladder stones \<5mm after medical treatment (Ursodeoxycholic acid ) for 1year . Imaging criteria ( large gallbladder stone \< 1cm diameter , gallbladder thickness \>3mm ) either symptomatic or asymptomatic . Exclusion Criteria: * Age \>18 years. Asymptomatic patients who improved after follow up and medical treatment . Biliary anomaly as choledochal cyst , biliary stricture. Common bile duct stones .
Where this trial is running
Sohag
- Sohag university hospital — Sohag, Egypt (RECRUITING)
Study contacts
- Study coordinator: Haithem D Ahmed, Resident
- Email: haithemdiaa@gmail.com
- Phone: 01005036082
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gallbladder Stone